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首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >Seroprevalence and sources of toxoplasmosis among Orang Asli (indigenous) communities in Peninsular Malaysia.
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Seroprevalence and sources of toxoplasmosis among Orang Asli (indigenous) communities in Peninsular Malaysia.

机译：马来西亚半岛红毛猩猩（土著）社区的血清阳性率和弓形虫源。

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This study aims to evaluate the current seroprevalence of toxoplasmosis among indigenous communities in Peninsular Malaysia and relate its association with epidemiological data. Overall seroprevalence of Toxoplasma gondii was 37.0% with 31.0% immunoglobulin (Ig) G, 1.8% IgM, and 4.2% seropositivity for both anti-Toxoplasma antibodies. Multivariate analysis showed that age above 12 years (odds ratio [OR] = 2.70, 95% confidence interval [CI] = 1.75-4.04, P < 0.001), using untreated river and mountain water supplies (OR = 1.50, 95% CI = 1.01-2.40, P = 0.050), and close proximity with cats (OR = 1.40, 95% CI = 1.10-1.76, P = 0.010) were factors associated with toxoplasmosis. Given the high seroprevalence of toxoplasmosis among these communities who live in poor socioeconomic conditions, a comprehensive health surveillance program and screening should be initiated among women of childbearing age and pregnant women during the antenatal period for early diagnosis and treatment. The role of domestic cats and environmental contamination with oocyst in soil and water has to be highlighted and addressed in future prevention strategies for these communities.
机译：这项研究的目的是评估马来西亚半岛土著社区目前弓形虫的血清流行率，并将其与流行病学数据相关联。两种弓形虫抗体的总弓形虫血清阳性率为37.0％，免疫球蛋白（Ig）G为31.0％，IgM为1.8％，血清阳性为4.2％。多变量分析表明，使用未经处理的河流和山区水源（OR = 1.50，95％CI = 12岁以上，年龄比[OR] = 2.70，95％置信区间[CI] = 1.75-4.04，P <0.001）。与弓形虫病相关的因素是1.01-2.40，P = 0.050），与猫的接近度（OR = 1.40，95％CI = 1.10-1.76，P = 0.010）。鉴于这些弓形虫病血清感染率较高，这些人群的社会经济状况较差，因此应在产前期妇女和孕妇中进行全面的健康监测和筛查，以进行早期诊断和治疗。在这些社区的未来预防策略中，必须强调和解决家猫的作用以及土壤和水中卵囊对环境的污染。

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