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首页> 外文期刊>The Australian and New Zealand journal of psychiatry >Are chronic fatigue and chronic fatigue syndrome valid clinical entities across countries and health-care settings?
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Are chronic fatigue and chronic fatigue syndrome valid clinical entities across countries and health-care settings?

机译：慢性疲劳和慢性疲劳综合症在各个国家和医疗机构是否有效？

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OBJECTIVE: The validity of the diagnosis of chronic fatigue syndrome and related chronic fatigue states remains controversial, particularly in psychiatry. This project utilized international epidemiological and clinical research data to test construct validity across diagnostic categories, health-care settings and countries. Relevant demographic, symptom and diagnostic data were obtained from 33 studies in 21 countries. The subjects had fatigue lasting 1-6 months (prolonged fatigue), or >6 months (chronic fatigue), or met diagnostic criteria for chronic fatigue syndrome. METHOD: Common symptom domains were derived by factor analytic techniques. Mean scores on each symptom factor were compared across diagnostic categories, health-care settings and countries. RESULTS: Data were obtained on 37,724 subjects (n = 20,845 female, 57%), including from population-based studies (n = 15,749, 42%), studies in primary care (n = 19 472, 52%), and secondary or specialist tertiary referral clinics (n = 2503, 7%). The sample included 2013 subjects with chronic fatigue, and 1958 with chronic fatigue syndrome. A five-factor model of the key symptom domains was preferred ('musculoskeletal pain/fatigue', 'neurocognitive difficulties', 'inflammation', 'sleep disturbance/fatigue' and 'mood disturbance') and was comparable across subject groups and settings. Although the core symptom profiles were similar, some differences in symptoms were observed across diagnostic categories, health-care settings and between countries. CONCLUSIONS: The construct validity of chronic fatigue and chronic fatigue syndrome is supported by an empirically derived factor structure from existing international datasets.
机译：目的：诊断慢性疲劳综合征和相关慢性疲劳状态的有效性仍存在争议，特别是在精神病学方面。该项目利用国际流行病学和临床研究数据测试了诊断类别，医疗机构和国家/地区的结构有效性。相关人口统计学，症状和诊断数据来自21个国家的33项研究。受试者的疲劳持续1-6个月（长时间疲劳），或> 6个月（慢性疲劳），或符合慢性疲劳综合征的诊断标准。方法：通过症状分析技术得出常见症状域。在诊断类别，医疗机构和国家/地区中比较了每种症状因素的平均得分。结果：获得了关于37,724名受试者（n = 20,845，女性，57％）的数据，包括基于人群的研究（n = 15,749，42％），初级保健研究（n = 19472，52％）以及二级或二级专科三级转诊诊所（n = 2503，7％）。样本包括2013年患有慢性疲劳的受试者和1958年患有慢性疲劳综合征的受试者。首选关键症状域的五因素模型（“肌肉骨骼疼痛/疲劳”，“神经认知障碍”，“炎症”，“睡眠障碍/疲劳”和“情绪障碍”），并且在各个受试者组和环境中具有可比性。尽管核心症状特征相似，但在诊断类别，医疗机构和国家之间观察到一些症状差异。结论：慢性疲劳和慢性疲劳综合症的结构效度得到了现有国际数据集经验性因素结构的支持。

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