...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The European Journal of Neuroscience >The role of the cerebellum in 'real' and 'imaginary' line bisection explored with 1-Hz repetitive transcranial magnetic stimulation.
【24h】

The role of the cerebellum in 'real' and 'imaginary' line bisection explored with 1-Hz repetitive transcranial magnetic stimulation.

机译：小脑在“真实”和“虚构”线平分中的作用通过1-Hz重复经颅磁刺激进行了探讨。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The role of the cerebellum is well characterized for many motor processes and for some cognitive tasks, although its contribution to lateralized spatial judgement has never been probed directly. To address this omission, we investigated the effects of cerebellar disruption on two different line bisection tasks in eight healthy subjects. Based on previous evidence of crossed cerebellar-cortical connections we predicted a shift in the perceived midline that would occur in opposite directions depending on the cerebellar hemisphere targeted. Repetitive transcranial magnetic stimulation (rTMS), given at 1-Hz (600 pulses), was used as a non-invasive way to interfere with processing in the cerebellar cortex. Performance was assessed for both 'physical' line bisection using a newly developed Landmark variant task and for 'mental' line bisection using number pairs. The effects for number line bisection were lateralized--left but not right cerebellar rTMS increased rightward errors, whereas for physical line bisection rTMS to either hemisphere did not affect performance. Effects due to neck muscle contraction and changes in eye position were ruled out with appropriate control stimulation sites, and eye-tracking. The results confirm the role of the cerebellum in spatial judgement, and, for the first time, demonstrate direct cerebellar involvement in the generation of the midline in 'imaginal' (number) space. The difference between number line and physical line bisection effects is discussed with reference to pre-existing models of cerebellar hemispheric specialization and functional topography.
机译：小脑的作用在许多运动过程和某些认知任务中已得到很好的表征，尽管从未直接探究其对侧向空间判断的贡献。为了解决这一遗漏，我们调查了八名健康受试者在两个不同的线对分任务中小脑干扰的影响。基于先前的小脑-皮质交叉连接的证据，我们预测视中线的移动会发生变化，具体取决于目标小脑半球。以1 Hz（600脉冲）的频率重复经颅磁刺激（rTMS）作为干扰小脑皮层中加工的一种非侵入性方式。使用新开发的Landmark变体任务对“物理”线平分和使用数字对的“心理”线平分的性能进行了评估。数字线平分的影响是侧向化的-左小脑rTMS而不是右小误差增加了向右误差，而对于物理线平分，rTMS到任一半球均不影响表现。通过适当的控制刺激部位和眼动追踪，可以排除由于颈部肌肉收缩和眼位变化引起的影响。结果证实了小脑在空间判断中的作用，并且首次证明小脑直接参与了“想象”（数字）空间中线的产生。参考小脑半球专业化和功能性地形的现有模型，讨论了数字线和物理线等分效应之间的差异。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号