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首页> 外文期刊>The Canadian journal of hospital pharmacy. >Physical Compatibility of Raniticline and Metoclopramide in 50-mL Minibags of Normal Saline
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Physical Compatibility of Raniticline and Metoclopramide in 50-mL Minibags of Normal Saline

机译：雷尼替林和甲氧氯普胺在50 mL生理盐水小袋中的物理相容性

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摘要

Ranitidine and metoclopramide are routinely given intravenously before surgical procedures that involve spinal or general anesthesia. Recently, another institution contacted our institution to request stability data to support the practice of routinely mixing ranitidine 50 mg and metoclopramide 10 mg in a 50-mL minibag of normal saline (0.9% sodium chloride) for IV administration before cesarean section. Before receiving this request, we had been unaware of this practice and assumed that these medications were to be administered either concurrently via the Y-site connector or consecutively. However, when questioned about the administration of these 2 medications, the nursing staff unanimously reported that this practice had been followed for more than 5 years on our institution's maternity ward, as well as in the adult surgical daycare unit. The authors contacted other large maternity centres in the region and discovered only one other site that was mixing ranitidine and metoclopramide before administration.
机译：雷尼替丁和甲氧氯普胺通常在涉及脊髓或全身麻醉的外科手术之前静脉内给予。最近，另一家机构联系我们机构，要求获得稳定性数据，以支持在剖宫产术前将50 mg雷尼替丁和10 mg甲氧氯普胺在50 mL生理盐水（0.9％氯化钠）小袋中常规混合的做法。在收到此请求之前，我们尚未意识到这种做法，并假设这些药物将通过Y站点连接器同时或连续给药。但是，当被问及这两种药物的给药方法时，护理人员一致报告说，在我们机构的产科病房以及成人外科日托病房中，这种做法已经执行了5年以上。作者联系了该地区的其他大型产科中心，发现在给药前仅另一个部位混合了雷尼替丁和甲氧氯普胺。

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