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首页> 外文期刊>The Canadian journal of clinical pharmacology =: Journal canadien de pharmacologie clinique >Management of hiv positive pregnancies in ontario: Current status
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Management of hiv positive pregnancies in ontario: Current status

机译：安大略省HIV阳性孕妇的管理：现状

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AIDS is one of the biggest health crises we face today. With nearly 20 million women infected with the virus that causes it, HIV, maternal transmission of HIV is increasingly becoming a serious concern and hindrance in stemming the proliferation of the disease. While an ever increasing number of pregnant women are being administered anti-retrovirals to mitigate the vertical transmission of the virus, little is known about the changing trends in the type of agents used and the duration of therapy.Objectives This paper attempts to identify any changes in the pattern of HIV management in pregnant women for the period of time spanning 1998 to 2005.Methods Data from the charts of 183 patients were reviewed. A retrospective, longitudinal and cross-sectional patient chart review was employed to obtain data. Parameters such as therapeutic management of HIV, class of drugs used and duration of treatment were assessed to identify any evolving patterns over the course of the study. Results It was seen that over time, the number of women receiving adequate therapeutic interventions has steadily increased. We also identified evolving trends in terms of the classes of anti-retrovirals employed and the duration of prophylaxis. Conclusion The strategies employed in the management of HIV positive pregnancies in Ontario, while evolving over time, were found to be in line with the guidelines in place. The information delivered by this study might enable the medical community to assess the progress in dealing with this challenge thus far and further fine tune the current strategy.
机译：艾滋病是我们今天面临的最大的健康危机之一。随着将近2000万妇女感染了导致其传播的病毒，艾滋病毒的孕产妇传播正日益成为阻碍该疾病扩散的严重关切和障碍。虽然越来越多的孕妇正在接受抗逆转录病毒药物以减轻病毒的垂直传播，但对所用药物类型和治疗持续时间的变化趋势知之甚少。以1998年至2005年这段时间的孕妇HIV管理模式为研究对象。方法回顾了183例患者图表中的数据。回顾性，纵向和横断面患者病历复习用于获得数据。评估了诸如HIV的治疗管理，使用的药物类别和治疗持续时间等参数，以识别研究过程中任何正在演变的模式。结果发现随着时间的流逝，接受适当治疗干预的妇女人数稳步增加。我们还根据所使用的抗逆转录病毒药物的种类和预防的持续时间确定了不断发展的趋势。结论在安大略省，对HIV阳性妊娠进行管理所采用的策略虽然随着时间的推移而发展，但与现行的指导方针是一致的。这项研究提供的信息可能使医学界能够评估迄今为止应对这一挑战的进展，并进一步调整当前的策略。

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