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首页> 外文期刊>The Canadian journal of hospital pharmacy. >Potentially Inappropriate Prescribing of Benzodiazepines for Older Adults and Risk of Falls During a Hospital Stay: A Descriptive Study
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Potentially Inappropriate Prescribing of Benzodiazepines for Older Adults and Risk of Falls During a Hospital Stay: A Descriptive Study

机译：老年人苯二氮卓类药物处方不当和住院期间跌倒的风险：一项描述性研究

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Background: Falls have been identified as a potential adverse event associated with the administration of psychotropic medications to older patients.Objective: The objective of this exploratory study was to examine the association between potentially inappropriate prescribing of benzodi-azepines, as defined by the Beers criteria, by older adults (at least 65 years of age) and the risk of having a fall during acute inpatient care.Methods: This 1-year retrospective cross-sectional study of discharges from a tertiary care hospital in Halifax, Nova Scotia, used pharmacy data to identify the prescription of benzodiazepines listed in the updated Beers criteria as being associated with an increased risk of falls. These data were linked with information on in-hospital falls from occurrence report forms.Results: For 5831 (58.1%) of the 10 044 discharges, the patient had received a prescription for at least one benzodiazepine during the hospital stay. A total of 574 falls were reported (for 374 patients), and 226 (39.4%) of the falls resulted in an injury. According to the Beers criteria, for 936 (9.3%) of the discharges, the patient had received a prescription for at least one potentially inappropriate benzodiazepine. However, there was no statistically significant difference between patients with a prescription for a potentially inappropriate benzodiazepine and those receiving an appropriate or no benzodiazepine in terms of occurrence of falls (4.5% versus 3.8%, p = 0.30) or fall-related injuries (2.6% versus 1.8%, p = 0.08). The median length of stay was about 3 days longer for the former group (9 versus 6 days, p < 0.001).Conclusions: The findings from the current study do not support use of the Beers criteria related to benzodiazepines alone for identifying patients at risk of falls or injuries.
机译：背景：跌倒已被确定为与老年患者服用精神药物有关的潜在不良事件。目的：本探索性研究的目的是研究根据比尔斯标准定义的苯并二氮杂仑可能不适当处方之间的关联方法：这项为期1年的回顾性横断面研究调查了新斯科舍省哈利法克斯市一家三级护理医院出院的患者，使用的是药房数据来识别更新的Beers标准中列出的与增加跌倒风险相关的苯二氮卓类药物的处方。这些数据与发病报告表中的院内摔倒信息相关联。结果：在10 044例出院中，有5831例（58.1％）的患者在住院期间已接受了至少一种苯二氮卓的处方。总共报告了574次跌倒（针对374名患者），其中226次（39.4％）跌倒造成了伤害。根据比尔斯（Beers）的标准，对于936例（9.3％）放电，患者已接受了至少一种可能不适当的苯二氮卓类药物的处方。然而，就跌倒发生率（4.5％比3.8％，p = 0.30）或与跌倒相关的伤害（2.6）而言，开具可能不适当的苯二氮卓类药物处方的患者与接受适当或不服用苯二氮卓类药物的患者之间无统计学差异。 ％对1.8％，p = 0.08）。前一组患者的中位住院时间延长了约3天（9天比6天，p <0.001）。结论：本研究的结果不支持仅使用与苯二氮卓类药物有关的Beers标准来识别有风险的患者跌落或受伤。

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