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首页> 外文期刊>The Canadian Journal of Neurological Sciences: le Journal Canadien des Sciences Neurologiques >Central Nervous System Tuberculosis Subsequent to Dural Grafting
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Central Nervous System Tuberculosis Subsequent to Dural Grafting

机译：硬脑膜移植术后中枢神经系统结核

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摘要

Despite modern diagnostic and treatment modalities, tuberculosis (TB) still remains a major worldwide health problem. Resurgence in developed countries is due mainly to infection with the human immunodeficiency virus, immigration from developing and/or underdeveloped countries, transmissions in hospitals and prisons and development of multidrug-resistant strains of TB. According to the estimates of World Health Organization, TB accounts for 7-8 million new cases every year and is responsible for 2.9 million deaths worldwide annually.2 Tuberculosis infection is encountered mainly in underdeveloped or developing countries, but increasing infection rate has recently been reported even in developed countries.3 As a developing country, it has been estimated that TB is increasing rather than decreasing since the 1970s in Turkey and is still a serious problem in this country.4 It has been estimated that neurological involvement of TB infection constitutes approximately 5-15 % of the cases, with a high predominance in children.5,6 Central nervous system (CNS) involvement including atypical forms have been reported and reviewed extensively in the literature.7-9 The bacteria are transmitted through inhalation of aerosolized droplets and CNS involvement occurs mainly by hematogenous route. Although iatrogenic CNS infections have been reported, such as after lumbar puncture,10 there has been no report of CNS TB after allogenic dural grafting.
机译：尽管采用了现代的诊断和治疗手段，但结核病（TB）仍然是世界范围内的主要健康问题。发达国家的复兴主要归因于人类免疫缺陷病毒的感染，来自发展中国家和/或不发达国家的移民，医院和监狱中的传播以及结核病多药耐药株的发展。根据世界卫生组织的估计，每年结核病新增病例为7-8百万，每年导致全世界290万人死亡。2结核病感染主要发生在不发达国家或发展中国家，但最近有报告指出感染率正在上升3作为发展中国家，据估计自1970年代以来，土耳其的结核病呈上升而不是下降的趋势，并且在该国仍然是一个严重的问题。4据估计，结核病感染的神经系统疾病约占5-15％的病例以儿童为主。5,6文献报道并广泛审查了包括非典型形式在内的中枢神经系统（CNS）的侵害。7-9细菌通过雾化雾滴的吸入传播中枢神经系统受累主要通过血行途径发生。尽管已有医源性中枢神经系统感染的报道，例如腰椎穿刺后[10]，但尚无异体硬脑膜移植后中枢神经系统结核的报道。

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