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Social class at birth and risk of psychosis

机译:出生时的社会阶层和患精神病的风险

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Background: Individuals with psychotic disorders are represented more in the lower social classes, yet there is conflicting evidence to whether these individuals drift into the lower social classes or whether lower social class is a risk factor for developing psychosis. The aim of this study was to examine whether the social class at birth is a risk factor for developing psychosis. Methods: We included individuals with a first episode of psychosis (FEP) whose social class at birth was determined from birth records. We employed a case-control study design and also compared the distribution of the social classes at birth of the cases to that of the general population. Results: A total of 380 individuals with an FEP and 760 controls were included in the case-control study. The odds ratio for developing an FEP associated with social class (low vs high) was.62 (95% confidence interval (CI):.46-.85, p .001), indicating that individuals from a lower social class at birth have a reduced risk of psychosis. Individuals born between 1961 and 1980 with an FEP were more likely to be from a higher social class at birth compared to the general population (60.8% vs 36.7%, X2 = 60.85, df = 1, p .001). However, this association was not observed for those born between 1981 and 1990. Conclusion: A higher social class at birth is associated with a greater risk for developing a psychotic disorder; however, this effect may show temporal variation.
机译:背景:精神病患者在较低的社会阶层中所占比例较高,但是有证据表明,这些人是否进入较低的社会阶层,或者较低的社会阶层是否是患精神病的危险因素。这项研究的目的是检查出生时的社会阶层是否是患精神病的危险因素。方法:我们纳入了患有首次精神病(FEP)的个体,其出生时的社会阶层是根据出生记录确定的。我们采用了病例对照研究设计,并将病例出生时的社会阶层分布与普通人群的分布进行了比较。结果:病例对照研究共纳入380名具有FEP的个体和760名对照。发展与社会阶层相关的FEP(低与高)的比值比为62(95%置信区间(CI):. 46-.85,p <.001),表明出生时来自较低社会阶层的人减少精神病的风险。与普通人群相比,1961年至1980年之间出生且患有FEP的个体更有可能来自较高的社会阶层(60.8%比36.7%,X2 = 60.85,df = 1,p <.001)。但是,对于1981年至1990年之间出生的人没有观察到这种关联。结论:出生时的社会阶层越高,患精神病的风险就越大;但是,此效果可能会显示时间变化。

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