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'Hikikomori': a new diagnosis or a syndrome associated with a psychiatric diagnosis?

机译:“ Hikikomori”:一种新的诊断或与精神病学诊断有关的综合症?

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This suggested that there may be further mutations yet to be discovered in the Japanese. As we have sequenced more than 40 Japanese families with ichthyo-sis vulgaris, there is now little possibility that further highly prevalent mutations will be found in the Japanese population. However, it is still possible that there might be multiple, further low-frequency FLG mutations discovered in the Japanese population. In addition, because of the relatively small sample size of this genetic study, further replication in association studies will be required for FLG mutations and asthma in Japan.
机译:这表明日语中可能还有其他突变尚未发现。由于我们已经对40多个患有鱼鳞病的日本家庭进行了测序,现在在日本人口中发现进一步高度流行的突变的可能性很小。但是,仍然有可能在日本人群中发现更多的低频FLG突变。另外,由于该基因研究的样本量相对较小,在日本,对于FLG突变和哮喘,将需要在关联研究中进一步复制。

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