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Expansion of HCV treatment access to people who have injected drugs through effective translation of research into public health policy: Scotland's experience

机译:通过有效地将研究转化为公共卫生政策,扩大向注射毒品者提供HCV治疗的机会:苏格兰的经验

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Seven years have elapsed since the Scottish Government launched its Hepatitis C Action Plan - a Plan to improve services to prevent transmission of infection, particularly among people who inject drugs (PWID), identify those infected and ensure those infected receive optimal treatment. The Plan was underpinned by industrial scale funding (around 100 million, in addition to the general NHS funding, will have been invested by 2015), and a web of accountable national and local multi-disciplinary multi-agency networks responsible for the planning, development and delivery of services. Initiatives ranged from the introduction of testing in specialist drug services through finger-prick blood sampling by non-clinical staff, to the setting of government targets to ensure rapid scale-up of antiviral therapy. The Plan was informed by comprehensive national monitoring systems, indicating the extent of the problem not just in terms of numbers infected, diagnosed and treated but also the more penetrative data on the number advancing to end-stage liver disease and death, and also through compelling modelling work demonstrating the potential beneficial impact of scaling-up therapy and the mounting cost of not acting. Achievements include around 50% increase in the proportion of the infected population diagnosed (38% to 55%); a sustained near two-and-a-half fold increase in the annual number of people initiated onto therapy (470 to 1050) with more pronounced increases among PWID (300 to 840) and prisoners (20 to 140); and reversing of an upward trend in the overall number of people living with chronic infection. The Action Plan has demonstrated that a Government-backed, coordinated and invested approach can transform services and rapidly improve the lives of thousands. Cited as "an impressive example of a national strategy" by the Global Commission on Drug Policy, the Scottish Plan has also provided fundamental insights of international relevance into the management of HCV among PWID. (C) 2015 The Authors. Published by Elsevier B.V.
机译:自苏格兰政府启动“丙型肝炎行动计划”以来已经过去了七年,该计划旨在改善服务以预防感染的传播,特别是在注射毒品者,发现感染者并确保感染者得到最佳治疗的人群中。该计划的基础是工业规模的资金(到2015年,将投资约1亿,除了NHS的一般资金),以及负责规划,发展的负责任的国家和地方多学科多机构网络网络和提供服务。倡议的范围从引入专门药物服务的测试到非临床人员通过手指采血取样,到设定政府目标以确保快速扩大抗病毒治疗的范围。该计划由全面的国家监测系统提供信息,表明问题的严重性不仅在于感染,诊断和治疗的人数方面,而且还包括关于晚期肝病和死亡人数的更具穿透性的数据,以及令人信服的建模工作证明了扩大疗法的潜在有益影响以及不采取行动的安装成本。成就包括诊断出的受感染人口比例增加了约50%(从38%增至55%);每年开始接受治疗的人数(470至1050)持续增加近两倍半,而PWID(300至840)和囚犯(20至140)的增加更为明显;慢性感染者总数的上升趋势正在逆转。该行动计划表明,政府支持,协调和投资的方法可以改变服务并迅速改善成千上万人的生活。苏格兰计划被全球毒品政策委员会称为“国家战略的杰出典范”,它还提供了国际上对PWID人群HCV管理相关性的基本见解。 (C)2015作者。由Elsevier B.V.发布

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