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首页> 外文期刊>The international journal of developmental biology >Transfer of an avian genetic reflex epilepsy by embryonic brain graft: a tissue autonomous process?
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Transfer of an avian genetic reflex epilepsy by embryonic brain graft: a tissue autonomous process?

机译:胚胎脑移植物转移禽遗传反射性癫痫:组织自主过程?

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摘要

Electroencephalographic characteristics and clinical symptoms of an avian genetic reflex epilepsy have been transferred from Fayoumi epileptic (Fepi) chickens to non-epileptic chickens by embryonic homotopic grafts of brain neuroepithelium. Transplanted tissues belonging to the prosencephalic vesicle transferred epileptic electrical features while tissues from the mesencephalic vesicle were responsible for seizure motor manifestations of the disease. Thus each of these tissues can express their own specificity when grafted separately in a normal host, but they co-operate to produce the complete epileptic phenotype when grafted together.
机译:禽类遗传反射性癫痫的脑电图特征和临床症状已通过脑神经上皮的胚胎同种异体移植物从Fayoumi癫痫(Fepi)鸡转移到了非癫痫性鸡。属于前脑小泡的移植组织转移了癫痫的电特征,而来自中脑小泡的组织则引起了该疾病的发作运动表现。因此,当将这些组织分别移植到正常宿主中时,这些组织中的每一个都可以表达自己的特异性,但是当移植在一起时,它们会共同产生完整的癫痫表型。

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