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Treatment costs of hepatitis C infection among injection drug users in Canada, 2006-2026.

机译:2006-2026年加拿大注射吸毒者中丙型肝炎感染的治疗费用。

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BACKGROUND: Canadian injection drug users (IDUs) are at high risk of hepatitis C virus infection (HCV). However, little is known about the costs associated with their HCV-related medical treatment. We estimated the medical costs of treating HCV-infected IDUs from 2006 to 2026. METHODS: We employed a Markov model of entry through birth or immigration to exposure-related behaviours or experiences, HCV infection, progression to HCV sequelae and mortality for active and ex-IDUs in Canada. We estimated direct and indirect treatment costs using data from the Ontario Case Costing Initiative (OCCI). RESULT: Approximately 137,000 IDUs will suffer from HCV-related disease each year until 2026. Applying the OCCI cost data to the prevalence of HCV-related disease from 2006 to 2026 yielded an estimated cost of Dollars 3.96 billion CND to treat HCV-infected IDUs. CONCLUSIONS: Substantial costs are associated with the treatment of HCV-related disease among Canadian IDUs. Given the lack of effective HCV prevention strategies in Canada, we must develop targeted evidence-based responses to prevent HCV transmission and ensure appropriate allocation of medical resources to meet the present and future treatment needs of HCV-infected IDUs.
机译:背景:加拿大注射吸毒者(IDU)感染丙型肝炎病毒(HCV)的风险很高。但是,对其与HCV相关的医疗相关的费用知之甚少。我们估计了从2006年到2026年治疗HCV感染的注射毒品的医疗费用。方法:我们采用马尔科夫模型,通过出生或移民进入与暴露相关的行为或经历,HCV感染,发展为HCV后遗症以及因活动而患病的人-加拿大的注射吸毒者。我们使用安大略省案例成本估算计划(OCCI)的数据估算了直接和间接治疗成本。结果:到2026年,每年约有137 000个IDU患有HCV相关疾病。将OCCI费用数据应用于2006年至2026年HCV相关疾病的患病率,估计治疗HCV感染IDU的费用为39.6亿加元。结论:加拿大注射毒品使用者中大量的费用与HCV相关疾病的治疗有关。鉴于加拿大缺乏有效的HCV预防策略,我们必须制定有针对性的循证对策,以预防HCV传播,并确保合理分配医疗资源,以满足目前和将来感染HCV的IDU的治疗需求。

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