首页> 外文期刊>The journal of alternative and complementary medicine: research on paradigm, practice, and policy >Hot topics in Chinese herbal drugs research documented in PubMed/MEDLINE by authors inside China and outside of China in the past 10 years: based on co-word cluster analysis.
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Hot topics in Chinese herbal drugs research documented in PubMed/MEDLINE by authors inside China and outside of China in the past 10 years: based on co-word cluster analysis.

机译:过去10年中国内外作者在PubMed / MEDLINE中记录的中草药研究热点:基于共词聚类分析。

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OBJECTIVE: This study aims to gain an overview of hot topics related to research focused on Chinese herbal drugs by authors inside China and outside of China in the past 10 years. METHODS: PubMed/MEDLINE was utilized in order to investigate and select research that was published on "Chinese herbal drugs" from 1998 to 2007, by authors located both inside and outside of China (MeSH terms were downloaded and ranked). MeSH terms that frequently appeared were identified and co-word analysis was carried out for two groups: (1) authors located in China, and (2) authors based outside of China, respectively. The hot topics concerning research into Chinese herbal drugs were concluded after cluster analysis and related document analysis. RESULTS: For authors in the China group versus those outside the China group, the search results were 4790 versus 2609 citations and approximately 40,000 versus 20,000 MeSH terms, respectively. The threshold value of highly frequent terms was set at 30 versus 20, and the cumulative frequency percentage of these terms was 40.92% versus 36.67%, respectively. Thus, 43 highly frequent MeSH terms were identified and 43 x 43 co-word matrices were acquired for each group. The appearance frequency of MeSH showed that most research focused on pharmacology, therapeutic application, phytotherapy, side-effects of Chinese herbal drugs, and identification of active chemical components in herbs. CONCLUSION: The hot topics are as follows: (1) anti-inflammatory activity, antioxidant activities, anticancer activity of phytogenic antineoplastic agents, and neuroprotective effects of Chinese herbal drugs; (2) common diseases treated with Chinese herbal drugs include hepatocirrhosis, diabetes, angina, chronic hepatitis B in China, and diabetes, asthma, prostate cancer, and hepatocirrhosis outside of China; (3) Chinese herbal nephropathy and acute hepatitis induced by Chinese herbal drugs; (4) PC-SPES (PDQ) for the treatment of prostate cancer, which was a hot topic for researchers located outside of China; (5) research on extraction of active components from medicinal plants; and finally (6) research related to the identification of the Chinese herbal drugs component with state-of-the-art technologies in China.
机译:目的:本研究旨在概述过去十年来国内外国内外有关中草药研究的热点话题。方法:使用PubMed / MEDLINE来调查和选择1998年至2007年间发表在《中国草药》上的国内外研究人员(MeSH术语已下载并排名)。确定了经常出现的MeSH术语,并对两组进行了共同词分析:(1)位于中国的作者和(2)分别位于中国境外的作者。经过聚类分析和相关文献分析,归纳出中草药研究的热点话题。结果:对于中国组和非中国组的作者,搜索结果分别是4790 vs 2609引文和大约40,000 vs 20000 MeSH词。高频率术语的阈值设置为30对20,这些术语的累积频率百分比分别为40.92%对36.67%。因此,每组确定了43个频繁的MeSH术语,并获得了43 x 43个共词矩阵。 MeSH的出现频率表明,大多数研究集中在药理学,治疗应用,植物疗法,中草药的副作用以及草药中有效化学成分的鉴定上。结论:热点问题如下:(1)植物抗肿瘤药的抗炎活性,抗氧化活性,抗癌活性以及中草药的神经保护作用; (2)用中草药治疗的常见疾病包括肝硬化,糖尿病,心绞痛,中国的慢性乙型肝炎,以及中国境外的糖尿病,哮喘,前列腺癌和肝硬化。 (三)中药肾病和中药诱发的急性肝炎; (4)PC-SPES(PDQ)用于治疗前列腺癌,这是中国以外研究人员的热门话题; (5)从药用植物中提取有效成分的研究;最后(6)是有关利用中国最先进技术鉴定中草药成分的研究。

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