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Ambulatory blood pressure monitoring in patients with chronic kidney disease and resistant hypertension

机译:慢性肾脏疾病和顽固性高血压患者的动态血压监测

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The role of ambulatory blood pressure (BP) monitoring (ABPM) has not been well-studied in patients with chronic kidney disease and resistant hypertension. In a retrospective study of the outpatient chronic kidney disease population, 156 patients with chronic kidney disease and resistant hypertension who had 24-hour ABPM and clinic BP measurements were identified. Resistant hypertension was defined as uncontrolled clinic BP while taking ≥3 medications including a diuretic or controlled BP while taking ≥4 medications. Within the study group, ambulatory BP <130/80mmHg was found in 35.9% of all patients. Only 6.4% had both ambulatory and clinic BP <130/80mmHg. Prevalence of white-coat hypertension, masked hypertension, and sustained hypertension were 29.5%, 5.8%, and 58.3%, respectively. Compared with patients with sustained hypertension, more patients in the white-coat hypertension group had low nocturnal average systolic BP (defined as nocturnal average systolic BP <100mmHg) (17.4% vs 0%) and low 24-hour average diastolic BP (defined as 24-hour average diastolic BP <60mmHg) (52.2% vs 22%, P<.01). ABPM provides more reliable assessment of BP in patients with chronic kidney disease and resistant hypertension.
机译:动态血压(BP)监测(ABPM)的作用在慢性肾脏病和顽固性高血压患者中尚未得到充分研究。在一项对门诊慢性肾脏病人群的回顾性研究中,确定了156名患有24小时ABPM和临床BP测量值的慢性肾脏病和顽固性高血压患者。抵抗性高血压被定义为在服用≥3种药物时不受控制的临床血压,包括在服用≥4种药物时利尿或受控的BP。在研究组中,在所有患者中有35.9%发现了动态血压<130 / 80mmHg。门诊和门诊血压均<130 / 80mmHg,仅有6.4%。白大衣高血压,蒙面高血压和持续高血压的患病率分别为29.5%,5.8%和58.3%。与持续性高血压患者相比,白大衣高血压组中更多的患者夜间平均收缩压低(定义为夜间平均收缩压<100mmHg)(17.4%比0%)和24小时平均舒张压低(定义为24小时平均舒张压BP <60mmHg)(52.2%vs 22%,P <.01)。 ABPM为慢性肾脏病和顽固性高血压患者的BP提供了更可靠的评估。

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