NF00659A(1), A(2), A(3), B-1 AND B-2, NOVEL ANTITUMOR ANTIBIOTICS PRODUCED BY ASPERGILLUS SP. NF 00659 .1. TAXONOMY, FERMENTATION, ISOLATION AND BIOLOGICAL ACTIVITIES

Suzuki K.; Yoshida H.; Fujita SI.; Nishikiori T.; Nakagawa T.; Kuwahara A.

首页> 外文期刊>The Journal of Antibiotics: An International Journal >NF00659A(1), A(2), A(3), B-1 AND B-2, NOVEL ANTITUMOR ANTIBIOTICS PRODUCED BY ASPERGILLUS SP. NF 00659 .1. TAXONOMY, FERMENTATION, ISOLATION AND BIOLOGICAL ACTIVITIES

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NF00659A(1), A(2), A(3), B-1 AND B-2, NOVEL ANTITUMOR ANTIBIOTICS PRODUCED BY ASPERGILLUS SP. NF 00659 .1. TAXONOMY, FERMENTATION, ISOLATION AND BIOLOGICAL ACTIVITIES

机译：NF00659A（1），A（2），A（3），B-1和B-2，由ASPERGILLUS SP生产的新型抗肿瘤药。 NF 00659 .1。分类法，发酵，分离和生物活性

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Five novel cytotoxic antibiotics, NF00659A(1) (1), A(2) (2), A(3) (3), B-1 (4) and B-2 (5) were discovered. They were isolated from a culture mycelium of Aspergillus sp. These compounds were proved to have 4,5-seco-tricyclic diterpene alpha-pyrone structure by spectroscopic analyses. They showed potent antitumor activities against human ovarian carcinoma A2780 and human colorectal adenocarcinoma SW480 cells, but did not show any antimicrobial activities at 1,000 mu g/ml against Gram-positive and Gram-negative bacteria, yeasts and fungi. [References: 10]

机译：发现了五种新型细胞毒性抗生素NF00659A（1）（1），A（2）（2），A（3）（3），B-1（4）和B-2（5）。它们是从曲霉菌种的菌丝体中分离出来的。通过光谱分析证明这些化合物具有4，5-seco-三环二萜α-吡喃酮结构。它们显示出对人卵巢癌A2780和人大肠腺癌SW480细胞有效的抗肿瘤活性，但在1,000μg / ml的浓度下对革兰氏阳性和革兰氏阴性细菌，酵母菌和真菌没有任何抗菌活性。 [参考：10]

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《The Journal of Antibiotics: An International Journal》 |1997年第4期|共4页
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Suzuki K.; Yoshida H.; Fujita SI.; Nishikiori T.; Nakagawa T.; Kuwahara A.;
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正文语种 eng
中图分类药学;药品;
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1. NF00659A(1), A(2), A(3), B-1 AND B-2, NOVEL ANTITUMOR ANTIBIOTICS PRODUCED BY ASPERGILLUS SP. NF 00659 .1. TAXONOMY, FERMENTATION, ISOLATION AND BIOLOGICAL ACTIVITIES [J] . Suzuki K., Yoshida H., Fujita SI., The Journal of Antibiotics: An International Journal . 1997,第4期

机译：NF00659A（1），A（2），A（3），B-1和B-2，由ASPERGILLUS SP生产的新型抗肿瘤药。 NF 00659 .1。分类法，发酵，分离和生物活性
2. THIOCORALINE, A NEW DEPSIPEPTIDE WITH ANTITUMOR ACTIVITY PRODUCED BY A MARINE MICROMONOSPORA .1. TAXONOMY, FERMENTATION, ISOLATION, AND BIOLOGICAL ACTIVITIES [J] . Romero F., Baz JP., Dequesada TG., The Journal of Antibiotics: An International Journal . 1997,第9期

机译：硫代胆碱，一种由海洋微孢子虫产生的具有抗活性的新的二肽1。分类法，发酵，分离和生物活性
3. GE3, A NOVEL HEXADEPSIPEPTIDE ANTITUMOR ANTIBIOTIC, PRODUCED BY STREPTOMYCES SP .1. TAXONOMY, PRODUCTION, ISOLATION, PHYSICO-CHEMICAL PROPERTIES, AND BIOLOGICAL ACTIVITIES [J] . Sakai Y., Tsujita T., Ochiai K., The Journal of Antibiotics: An International Journal . 1997,第8期

机译：GE3，一种新的十六肽抗真菌药，由链霉菌SP 1..1生产。分类法，生产，分离，理化性质和生物活性
4. Sugar-Rich Hydrolyzates from Coffee Pulp Waste which Produced under Solid State Fermentation by Pestalotiosis sp. VM9 and Aspergillus sp. VTM5, and Its Efficiency as Medium for Single Cell Protein Saccharomyces cerevisiae [C] . Syafiq Ubaidillah, Kahar Muzakhar Annual Basic Science International Conference . 2019

机译：来自咖啡纸浆废物的富含糖水解物，该浆料废物通过荚膜病SP通过固态发酵产生。 VM9和Aspergillus sp。 VTM5，其作为单细胞蛋白酿酒酵母酿酒酵母的培养基
5. Correction: Singh, M.P., et al. Cytoskyrins and Cytosporones Produced by Cytospora sp. CR200: Taxonomy, Fermentation and Biological Activities [O] . Maya P. Singh, Jeffrey E. Janso, Sean F. Brady 2018

机译：校正：Singh，M.P.等。 Cytospora sp。生产的Cytoskyrins和Cytosporones。 CR200：分类学，发酵和生物活动
6. Gilvocarcins, new antitumor antibiotics. 1. Taxonomy, fermentation, isolation and biological activities. [O] . HIROFUMI NAKANO, YUZURU MATSUDA, KUNIO ITO, 1981

机译：Gilvocarcins，新的抗肿瘤抗生素。 1.分类，发酵，分离和生物活性。

NF00659A(1), A(2), A(3), B-1 AND B-2, NOVEL ANTITUMOR ANTIBIOTICS PRODUCED BY ASPERGILLUS SP. NF 00659 .1. TAXONOMY, FERMENTATION, ISOLATION AND BIOLOGICAL ACTIVITIES

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