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首页> 外文期刊>The Journal of Antibiotics: An International Journal >Nothramicin, a new anthracycline antibiotic from Nocardia sp. MJ896-43F17
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Nothramicin, a new anthracycline antibiotic from Nocardia sp. MJ896-43F17

机译:Nothramicin,一种来自Nocardia sp。的新型蒽环类抗生素。 MJ896-43F17

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摘要

A new antibiotic designated nothramicin was isolated from the culture broth of Nocardia sp. MJ896-43F17 which was closely related to Nocardia brasiliensis. It was isolated by the Diaion HP-20 column chromatography, butyl acetate extraction and purified by HPLC. It inhibited the growth of mycobacteria at the concentration of 1.56 similar to 25 mu g/ml. Nothramicin was revealed to be a new member of anthracycline antibiotics by the various spectroscopies. [References: 18]
机译:从诺卡氏菌属(Nocardia sp。)的培养液中分离出一种新的抗生素,命名为Notthramicin。与巴西诺卡氏菌密切相关的MJ896-43F17。通过Diaion HP-20柱色谱分离,乙酸丁酯萃取,并通过HPLC纯化。它以接近25μg / ml的1.56浓度抑制了分枝杆菌的生长。各种光谱学表明,诺沙米星是蒽环类抗生素的新成员。 [参考:18]

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