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首页> 外文期刊>The Journal of Antibiotics: An International Journal >Allantofuranone, a new antifungal antibiotic from Allantophomopsis lycopodina IBWF58B-05A.
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Allantofuranone, a new antifungal antibiotic from Allantophomopsis lycopodina IBWF58B-05A.

机译:Allantofuranone,一种来自Allantophomopsis lycopodina IBWF58B-05A的新型抗真菌抗生素。

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摘要

In a screening for new bioactive compounds, the extract of Allantophomopsis lycopodina strain IBWF58B-05A, an imperfect ascomycete, was found to exhibit strong but rather selective antibiotic activity against Paecilomyces variotii. The bioactivity-guided isolation yielded allantofuranone, a new and uncommon gamma-lactone. This compound showed antifungal activity against P. variotii and Penicillium species. This paper describes the isolation, structure elucidation and biological characteristics of allantofuranone.
机译:在筛选新的生物活性化合物时,发现不完美的子囊拟南芥lycopodina菌株IBWF58B-05A的提取物表现出了强大的但对选择性拟青霉具有选择性的抗生素活性。生物活性指导下的分离产生了新的和不常见的γ-内酯-四氢呋喃酮。该化合物显示了对水痘假单胞菌和青霉菌的抗真菌活性。本文描述了Allantofuranone的分离,结构解析和生物学特性。

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