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首页> 外文期刊>The Journal of Antibiotics: An International Journal >Nafuredin, a Novel Inhibitor of NADH-fumarate Reductase,Produced by Aspergillus niger FT-0554
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Nafuredin, a Novel Inhibitor of NADH-fumarate Reductase,Produced by Aspergillus niger FT-0554

机译:Nafuredin,一种新型抑制剂,NADH-富马酸酯还原酶,由黑曲霉FT-0554生产

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摘要

A novel compound, nafuredin,was isoalted as an inhibitor of anaerobic electron transport (NADH-fumarate reductase). It was obtained from culture broth of Aspergillus niger FT-0554 isolated from a marine sponge. The structure was elucidated as an epoxy-#delta#-lactone with an attached methylated olefinic side chain on the basis of spectral analysis.
机译:一种新型化合物,呋喃丁,被认为是厌氧电子传输抑制剂(NADH-富马酸酯还原酶)。它是从分离自海洋海绵的黑曲霉FT-0554的培养液中获得的。在光谱分析的基础上,将该结构阐明为具有连接的甲基化的烯烃侧链的环氧-δ-内酯。

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