Bhimamycin Aapprox E and Bhimanone:Isolation,Structure Elucidation and Biological Activity of Novel Quinone Antibiotics form a Terrestrial Streptomycete

Serge Fotso; Rajendra P.Maskey; Iris Grun-Wollny; Klaus-Peter Schulaz; Morton Munk; Hartmut Laatsch

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Bhimamycin Aapprox E and Bhimanone:Isolation,Structure Elucidation and Biological Activity of Novel Quinone Antibiotics form a Terrestrial Streptomycete

机译：Bhimamycin Aapprox E和Bhimanone：新型醌类抗生素的分离，结构解析和生物活性

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From the ethyl acetateextract of a terrestrial Streptomycete isolate,five new quinone antinbiotics,bhimamycin A(2a),B(2b),C(3c),D(5a),E(7) and th enew tetralone bhimanone (8) were isolated together with the known microbial products cyrysophanol(1a),aloesaponarin II(1b),3,8-dihydroxy-1-methylanthraquinone-2-carboxylic acid(1c),adenosine,2'-deoxyadenosine,phenylacetamide,and 2-(p-hydroxyphenyl)ethanol.the strutures of these natural products were deduced from the spectral data and confirmed by comparison with relatd compounds form the literature and by synthesis.

机译：从陆生链霉菌分离物中的乙酸乙酯提取物中分离出五种新的醌类抗生素，比奇霉素A（2a），B（2b），C（3c），D（5a），E（7）和新的四氢萘醌比曼酮（8）。连同已知的微生物产品cyssophanol（1a），aloesaponarin II（1b），3,8-二羟基-1-甲基蒽醌-2-羧酸（1c），腺苷，2'-脱氧腺苷，苯基乙酰胺和2-（对-从光谱数据推导出这些天然产物的结构，并通过与文献中相关化合物的比较和合成来证实。

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《The Journal of Antibiotics: An International Journal》 |2003年第11期|共11页
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Serge Fotso; Rajendra P.Maskey; Iris Grun-Wollny; Klaus-Peter Schulaz; Morton Munk; Hartmut Laatsch;
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1. Bhimamycin Aapprox E and Bhimanone:Isolation,Structure Elucidation and Biological Activity of Novel Quinone Antibiotics form a Terrestrial Streptomycete [J] . Serge Fotso, Rajendra P.Maskey, Iris Grun-Wollny, The Journal of Antibiotics: An International Journal . 2003,第11期

机译：Bhimamycin Aapprox E和Bhimanone：新型醌类抗生素的分离，结构解析和生物活性
2. Bhimamycin A similar to E and bhimanone: Isolation, structure elucidation and biological activity of novel quinone antibiotics from a terrestrial streptomycete [J] . Fotso S., Maskey RP., Grun-Wollny I., The Journal of Antibiotics: An International Journal . 2003,第11期

机译：Bhimamycin A与E和bhimanone相似：来自陆生链霉菌的新型醌类抗生素的分离，结构解析和生物学活性
3. Bhimamycin A to approximately E and bhimanone: isolation, structure elucidation and biological activity of novel quinone antibiotics from a terrestrial Streptomycete. [J] . Fotso S, Maskey RP, Grun Wollny I, The Journal of Antibiotics: An International Journal . 2003,第11期

机译：Bhimamycin A到E和bhimanone：从陆生链霉菌中分离出来的新型醌类抗生素，对其结构进行阐明，并具有生物学活性。
4. Structure Elucidation of Novel Natural Products of Streptomycetes by Molecular Networking and Ion-Mobility Spectrometry [C] . Andrew R. Johnson, Chan Gao, Marie Elliott, ASMS Conference on Mass Spectrometry and Allied Topics . 2014

机译：分子网络和离子迁移光谱法的结构阐明了链霉菌的新型天然产物
5. Isolation and structure elucidation of biologically active compounds from terrestrial and fungal organisms [D] . Habib, Eman S. 2010

机译：陆生和真菌生物中生物活性化合物的分离和结构解析
6. Stemodane Diterpenes and Diterpenoids: Isolation Structure Elucidation Biogenesis Biosynthesis Biological Activity Biotransformations Metabolites and Derivatives Biological Activity Rearrangements [O] . Francesca Leonelli, Luisa Maria Migneco, Alessio Valletta, 2021

机译：苯二甲烷和二萜：分离结构阐明生物发生生物合成生物活性生物转化代谢物和衍生物生物活性重排
7. Kettapeptin: Isolation, Structure Elucidation and Activity of a New Hexadepsipeptide Antibiotic from a Terrestrial Streptomyces sp. [O] . Rajendra P Maskey, Serge Fotso, Madhumati Sevvana, 2006

机译：Kettapeptin：从陆生链霉菌SP中的新六己二肽抗生素的分离，结构阐明和活性。
8. Metorphamide: Isolation, Structure, and Biologic Activity of an Amidated Opioid Octapeptide from Bovine Brain [R] . Weber, E., Esch, F. S., Bohlen, P., 1983

机译：metorphamide：牛脑中amidated阿片类八肽的分离，结构和生物活性

Bhimamycin Aapprox E and Bhimanone:Isolation,Structure Elucidation and Biological Activity of Novel Quinone Antibiotics form a Terrestrial Streptomycete

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