Cytosine-type nucleosides from marine-derived Streptomyces rochei 06CM016

Aksoy Semiha Cetinel; Uzel Atac; Bedir Erdal

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Cytosine-type nucleosides from marine-derived Streptomyces rochei 06CM016

机译：海洋来源的罗氏链霉菌06CM016的胞嘧啶核苷

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Rocheicoside A (3), a nucleoside analog possessing a novel 5-(hydroxymethyl)-5-methylimidazolidin-4-one substructure, was isolated from marine-derived actinomycete Streptomyces rochei 06CM016, together with a new (4) and three known compounds. Structures of the new metabolites were elucidated by one-dimensional (H-1 and C-13) and 2D NMR (COSY, HMQC and HMBC) and HR-TOF-MS analyses. All the metabolites exhibited significant antimicrobial activity. A plausible mechanism was proposed for compound 3's formation from amicetin.

机译：从海洋来源的放线菌罗氏链霉菌06CM016中分离出一种具有新型5-（羟甲基）-5-甲基咪唑啉酮-4-一亚结构的核苷类似物Rocheicoside A（3），以及一种新的（4）和三种已知化合物。通过一维（H-1和C-13）和2D NMR（COSY，HMQC和HMBC）和HR-TOF-MS分析阐明了新代谢物的结构。所有代谢物均显示出显着的抗菌活性。有人提出了从阿米斯汀形成化合物3的合理机制。

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《The Journal of Antibiotics: An International Journal》 |2016年第1期|共6页
作者
Aksoy Semiha Cetinel; Uzel Atac; Bedir Erdal;
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正文语种 eng
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1. Cytosine-type nucleosides from marine-derived Streptomyces rochei 06CM016 [J] . Aksoy Semiha Cetinel, Uzel Atac, Bedir Erdal The Journal of Antibiotics: An International Journal . 2016,第1期

机译：海洋来源的罗氏链霉菌06CM016的胞嘧啶核苷
2. Anti-Mycobacterial Nucleoside Antibiotics from a Marine-Derived Streptomyces sp. TPU1236A [J] . Hiroyuki Yamazaki, Jordan Zjawiony, Kazuyo Ukai, Marine Drugs . 2014,第12期

机译：海洋衍生的链霉菌sp。的抗分枝杆菌核苷抗生素。 TPU1236A
3. Farnesides A and B, Sesquiterpenoid Nucleoside Ethers from a Marine-Derived Streptomyces sp., strain CNT-372 from Fiji [J] . Ilan Ella Zafrir, Torres Manuel R., Prudhomme Jacques, Journal of natural products . 2013,第9期

机译：Farnesides A和B，来自海洋的链霉菌属物种的倍半萜类核苷醚，来自斐济的CNT-372菌株
4. Quantitation of nucleosides and nucleoside triphosphates using LC-MS/MS in bioanalysis [C] . Nerea Ferreiros, Dominique Thomas, Nikolas Herold, International Mass Spectrometry Conference . 2014

机译：使用LC-MS / MS在生物分析中定量核苷和核苷三磷酸酯
5. Natural products biosynthesis: I. Geosmin biosynthesis in Streptomyces coelicolor A3(2) and Nostoc punctiforme PCC 73102. II. Pentalenolactone biosynthetic pathway in Streptomyces avermitilis. [D] . Jiang, Jiaoyang. 2009

机译：天然产物的生物合成：I. coelicolor链霉菌A3（2）和点状诺氏菌PCC 73102中的土臭素生物合成。阿维链霉菌中的戊烯戊内酯生物合成途径。
6. New Metabolites From the Co-culture of Marine-Derived Actinomycete Streptomyces rochei MB037 and Fungus Rhinocladiella similis 35 [O] . Meilin Yu, Yingxin Li, Shivakumar P. Banakar, -1

机译：海洋来源的放线菌链霉菌MB037和真菌Rhinocladiella similis共培养的新代谢物35
7. New Metabolites From the Co-culture of Marine-Derived Actinomycete Streptomyces rochei MB037 and Fungus Rhinocladiella similis 35 [O] . Meilin Yu, Yingxin Li, Shivakumar P. Banakar, 2019

机译：来自海洋衍生的放射素瘤细胞的共同培养的新代谢物链霉菌罗奇霉菌MB037和真菌rhinocladiella similis 35

Cytosine-type nucleosides from marine-derived Streptomyces rochei 06CM016

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