Drug eruption induced by gonadotropin-releasing hormone analogs accompanying radiation-recall phenomenon

Mika OSHIMA; Kazutoshi MURAO; Takeshi ISHIGAMI; Yoshiaki KUBO

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Drug eruption induced by gonadotropin-releasing hormone analogs accompanying radiation-recall phenomenon

机译：促性腺激素释放激素类似物引起的辐射与召回现象

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Goserelin acetate and leuprorelin acetate are gonadotropin-releasing hormone analogs (GnRHA), and are used to suppress production of the sex hormones in the treatment of breast and prostate cancer. Although several cases of granulomatous reactions at injection sites have been reported, generalized drug eruptions induced by GnRHA are rare. Herein, we report a rare case of drug eruption induced by goserelin acetate. In addition to generalized maculopapular eruption, the patient exhibited intense erythema in the previously irradiated area, which was considered to be radiation-recall phenomenon.

机译：乙酸戈瑞瑞林和乙酸亮丙瑞林是促性腺激素释放激素类似物（GnRHA），用于在乳腺癌和前列腺癌的治疗中抑制性激素的产生。尽管已经报道了在注射部位发生肉芽肿反应的几种情况，但由GnRHA引起的全身性药疹很少见。在本文中，我们报告了由醋酸戈舍瑞林引起的药物喷发的罕见情况。除了全身性黄斑丘疹外，该患者在先前受照射的部位还表现出强烈的红斑，这被认为是放射回想现象。

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《The Journal of dermatology》 |2012年第12期|共2页
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Mika OSHIMA; Kazutoshi MURAO; Takeshi ISHIGAMI; Yoshiaki KUBO;
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正文语种 eng
中图分类皮肤病学与性病学;
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1. Drug eruption induced by gonadotropin-releasing hormone analogs accompanying radiation-recall phenomenon [J] . Mika OSHIMA, Kazutoshi MURAO, Takeshi ISHIGAMI, The Journal of dermatology . 2012,第12期

机译：促性腺激素释放激素类似物引起的辐射与召回现象
2. Effect of the timing of controlled internal drug-releasing device insertion on the gonadotropin-releasing hormone-induced luteinizing hormone surge and ovulatory response [J] . G A Perry B L Perry Journal of Animal Science . 2009,第12期

机译：控制性内部释放药物装置的插入时间对促性腺激素释放激素诱导的黄体生成素激增和排卵反应的影响
3. Effect of the timing of controlled internal drug-releasing device insertion on the gonadotropin-releasing hormone-induced luteinizing hormone surge and ovulatory response [J] . Perry G. A., Perry B. L. Journal of Animal Science . 2009,第12期

机译：控制性内部释放药物的插入时机对促性腺激素释放激素诱导的黄体生成素激增和排卵反应的影响
4. Using prostaglandin F2a and gonadotropin-releasing hormone simultaneously 7 d prior to Ovsynch increased first-service pregnancies per artificial insemination compared to Presynch-14/Ovsynch [C] . Annual Conference of The American Association of Bovine Practitioners . 2018

机译：在Ovsynch之前同时使用前列腺素F2A和促性腺激素释放激素在Ovsynch之前同时进行7天，而与PRESYNCH-14 / OVSYNCH相比，每个人工授精的第一阶段性妊娠增加
5. Signal transduction of gonadotropin-releasing hormone-induced gonadotropin subunit and growth hormone gene expression in the goldfish pituitary. [D] . Klausen, Christian. 2004

机译：金鱼垂体中促性腺激素释放激素诱导的促性腺激素亚基和生长激素基因表达的信号转导。
6. Long-term effects and significant adverse drug reactions (ADRs) associated with the use of gonadotropin-releasing hormone analogs (GnRHa) for central precocious puberty: a brief review of literature [O] . De Sanctis Vincenzo, T Soliman Ashraf, Di Maio Salvatore, 2020

机译：与促性腺激素释放激素类似物（GnRHa）用于中枢性性早熟相关的长期影响和重大药物不良反应（ADR）：文献综述
7. Metabolic Health in Short Children Born Small for Gestational Age Treated With Growth Hormone and Gonadotropin-Releasing Hormone Analog: Results of a Randomized, Dose-Response Trial [O] . van der Steen, Manouk, Lem, Annemieke J., van der Kaay, Danielle C. M., 2015

机译：生长激素和促性腺激素释放激素类似物治疗的妊娠期矮小儿童的代谢健康：一项随机剂量反应试验的结果

Drug eruption induced by gonadotropin-releasing hormone analogs accompanying radiation-recall phenomenon

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