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首页> 外文期刊>The journal of microbiology >Genomic diversity of Legionella pneumophila serogroup 1 from environmental water sources and clinical specimens using pulsed-field gel electrophoresis (PFGE) from 1985 to 2007, Korea
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Genomic diversity of Legionella pneumophila serogroup 1 from environmental water sources and clinical specimens using pulsed-field gel electrophoresis (PFGE) from 1985 to 2007, Korea

机译：1985年至2007年，使用脉冲场凝胶电泳（PFGE）从环境水源和临床标本中分离到的嗜肺军团菌血清群1的基因组多样性

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The molecular typing of 202 Legionella pneumophila sg 1 isolates obtained from environmental water sources and clinical specimens from 1985 to 2007 was conducted using pulsed-field gel electrophoresis (PFGE). In this study, a total of 212 isolates were grouped into 35 different PFGE types and Type 1 was the predominant type, accounting for 28.7% in PFGE types. Type 1 and Type 8 were observed continuously from 1985 to 2007. In the analysis of the distribution of PFGE types in six geographic regions (Seoul-Incheon, Gangwon, Chungcheong, Gyeongsang, Jeolla, and Jeju), Type 1 was predominant throughout four regions except for Jeolla and Jeju, and Type 6 was observed in four regions except two regions (Gangwon and Jeju). Six clinical isolates belonged to PFGE Type 1, Type 6, Type 9, and Type 15. Type 1 among these types, was isolated from 3 patients with confirmed nosocomial infection at the hospital and Type 6, Type 9, and Type 15 were isolated 3 patients with suspected community-acquired infection. Type R, PFGE pattern of L. pneumophila sg 1 (ATCC 33152, Philadelphia-1), was not observed in the isolates evaluated in this study. Therefore, our results suggest that PFGE Type 1 was very prevalent in the environmental and clinical isolates in Korea. Type 1 was distributed continuously for many years throughout Korea.
机译：使用脉冲场凝胶电泳（PFGE）进行了1985年至2007年从环境水源和临床标本中获得的202株嗜肺军团菌sg 1分离株的分子分型。在这项研究中，总共212个分离株被分为35种不同的PFGE类型，其中1型为主要类型，占PFGE类型的28.7％。从1985年至2007年连续观察到1型和8型。在分析六个地理区域（首尔-仁川，江原，忠清，庆尚，全罗和济州）的PFGE类型分布时，1型在四个地区中占主导地位。除了全罗（Jeolla）和济州（Jeju）外，在两个地区（江原道（Gangwon）和济州（Jeju））之外的四个地区都观察到6型。从医院确诊的3例患者中分离出6种临床分离株，分别属于PFGE 1型，6型，9型和15型。其中1型是从医院确诊的3例患者中分离出来的，6型，9型和15型是分离的3。怀疑是社区获得性感染的患者。在本研究评估的分离物中未观察到R. pneumophila sg 1（ATCC 33152，Philadelphia-1）的PFGE型。因此，我们的结果表明，PFGE 1型在韩国的环境和临床分离株中非常普遍。 1型在韩国连续多年分发。

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