Knowledge about the oxytocin (OT) system in the brain has increased greatly over the past decade. Although this neuropeptide is best known for its peripheral effects, direct modulation of central nervous system (CNS) areas has also been implicated in OT's actions, which include a major role in a wide range of affiliative behaviors.16"24 Often referred to as the "social bonding" hormone, speculations are being made as to its applications and potential uses in enhancing human relationships. Alterations in the OT system have been implicated in several neuropsychiatric disorders.25 Multiple types of psychopathology manifest in deficits in social functioning, including inability to maintain interpersonal relationships and engage in socially appropriate behavior.
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