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首页> 外文期刊>The Journal of neuropsychiatry and clinical neurosciences >Depression, avolition, and attention disorders in patients with schizophrenia: associations with verbal memory efficiency.
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Depression, avolition, and attention disorders in patients with schizophrenia: associations with verbal memory efficiency.

机译：精神分裂症患者的抑郁，精神错乱和注意力障碍：与言语记忆效率的关联。

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摘要

The authors undertook a study of the clinical correlates of verbal memory deficits in schizophrenia. The first purpose was to replicate the finding of a significant association between depression and impairment in the deep encoding memory processes. The second purpose was to test the hypothesis that certain clinical symptoms--avolition, disorders of attention--also play a role in verbal memory impairment, distinct from a global negative symptomatology score. Forty-one patients with schizophrenia underwent a memory task including forward digit span and learning lists of words with different levels of semantic organization. Regression analyses revealed that the depression score was associated with the total number of recalled words, whereas the global negative symptom score was not. Depression score was not associated with the forward digit span, a measure of superficial serial encoding processes. An analysis of individual symptoms from the Scale for the Assessment of Negative Symptoms (SANS) indicated that avolition was associated with several memory scores, suggesting a pervasive effect of this symptom. Attention disorders were associated with impaired efficiency in serial learning, but not with word recall efficiency. It is suggested that more consideration should be given to depression and motivation in the investigation of cognitive impairment in schizophrenia, as well as in cognitive remediation strategies.
机译：作者对精神分裂症的言语记忆缺陷的临床相关性进行了研究。第一个目的是复制在深层编码记忆过程中抑郁与障碍之间存在显着关联的发现。第二个目的是检验以下假设：某些临床症状-意志失调，注意力障碍-也会在言语记忆障碍中起作用，这与总体阴性症状评分不同。 41名精神分裂症患者接受了一项记忆任务，包括前向数字跨度和学习具有不同语义组织水平的单词列表。回归分析表明，抑郁得分与回忆单词的总数有关，而总体负面症状得分与回忆单词的数量无关。抑郁分数与前指跨度（表观串行编码过程的度量）无关。从阴性症状评估量表（SANS）中对单个症状进行的分析表明，意志消退与多个记忆评分相关，这表明这种症状普遍存在。注意障碍与连续学习效率受损有关，但与单词回忆效率无关。建议在精神分裂症的认知障碍研究以及认知补救策略中应更多考虑抑郁和动机。

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