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首页> 外文期刊>The journal of pain: official journal of the American Pain Society >Assessing controlled substance prescribing errors in a pediatric teaching hospital: an analysis of the safety of analgesic prescription practice in the transition from the hospital to home.
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Assessing controlled substance prescribing errors in a pediatric teaching hospital: an analysis of the safety of analgesic prescription practice in the transition from the hospital to home.

机译:评估儿科教学医院的控制药物处方错误:从医院到家庭的过渡过程中止痛处方的安全性分析。

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摘要

Iatrogenic errors producing serious and often preventable injury occur frequently in hospitalized patients, particularly in children. Little is known about the epidemiology of analgesic medication errors in patients being discharged from the hospital. The goal of this study was to describe the epidemiology of controlled substance prescription errors by physicians-in-training for children being discharged from the hospital. We conducted a prospective, observational study of the analgesic prescriptions and discharge forms of 241 pediatric patients discharged from a Children's Center of a major urban teaching hospital from November 2003 to April 2004. All patients who were actively followed by the Pediatric Pain Service at the time of their discharge and were discharged with an analgesic prescription were included in the study. Primary outcome variables were the percentage of prescriptions that contained at least 1 medication error or potential adverse drug event. Errors were defined using the Institute for Safe Medication Practices' (ISMP) List of Error-Prone Abbreviations, Symbols, and Dose Designations, literature review, expert panel consensus, and the Johns Hopkins Department of Pharmacy hospital formulary. Two hundred forty-one patients who received 314 prescriptions were included in this study. Prescription errors were common; 257 of 314 (82%) of the prescriptions examined contained 1 or more errors. The most common errors were missing or wrong patient weight (n = 127, 77%), incomplete dispensing information (n = 167, 53%), and no or wrong date on prescription (n = 19, 6%). Nine prescriptions (2.9%) had the potential for significant medical injury and were considered potential adverse drug events. Discharge prescription errors for children requiring potent, opioid analgesic drugs in the management of pain are common, and nearly 3% could cause significant harm. The high rate of prescribing errors highlights the importance of developing, testing and implementing effective error-prevention strategies, especially in high-risk medications such as narcotics. PERSPECTIVE: Narcotic prescriptions written by trainees at discharge from a pediatric hospital are error prone and nearly 3% have the potential to cause significant harm. With a low therapeutic profile, the hospital may consider a review/verification process to reduce the risk of patient harm.
机译:住院患者,特别是儿童中,经常发生引起严重且通常可以预防的伤害的医源性错误。对于出院患者中止痛药物错误的流行病学知之甚少。这项研究的目的是描述接受培训的医师对出院儿童进行控制药物处方错误的流行病学。我们对2003年11月至2004年4月从一家主要城市教学医院的儿童中心出院的241例儿科患者的镇痛处方和出院形式进行了前瞻性观察研究。当时所有患者均由儿科疼痛服务中心积极跟踪他们的出院和镇痛药出院被纳入研究。主要结果变量是包含至少1种用药错误或潜在不良药物事件的处方百分比。使用安全用药协会(ISMP)的错误-错误缩写,符号和剂量名称清单,文献综述,专家小组共识以及约翰·霍普金斯大学药房医院处方来定义错误。本研究纳入了接受314张处方的241位患者。处方错误很常见;所检查的314个处方中有257个(82%)包含1个或更多个错误。最常见的错误是患者体重缺失或错误(n = 127,77%),配药信息不完整(n = 167,53%)以及开药日期无误或错误(n = 19,6%)。九种处方(占2.9%)有可能造成重大医疗伤害,被认为是潜在的不良药物事件。对于需要有效的阿片类镇痛药治疗疼痛的儿童,出院处方错误很普遍,将近3%的儿童可能会造成重大伤害。处方错误率很高,凸显了开发,测试和实施有效的错误预防策略的重要性,尤其是在麻醉药品等高风险药物中。观点:出院时出院的学员所写的麻醉处方容易出错,将近3%的人有可能造成重大伤害。对于低治疗水平的医院,医院可能会考虑进行复查/验证过程以减少患者受到伤害的风险。

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