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首页> 外文期刊>The Journal of Nutritional Biochemistry >The role of dietary fatty acids in the pathology of metabolic syndrome.
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The role of dietary fatty acids in the pathology of metabolic syndrome.

机译：膳食脂肪酸在代谢综合征的病理中的作用。

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Dysfunctional lipid metabolism is a key component in the development of metabolic syndrome, a very frequent condition characterized by dyslipidemia, insulin resistance, abdominal obesity and hypertension, which are related to an elevated risk for type 2 diabetes mellitus. The prevalence of metabolic syndrome is strongly associated with the severity of obesity; its physiopathology is related to both genetics and food intake habits, especially the consumption of a high-caloric, high-fat and high-carbohydrate diet. With the progress of scientific knowledge in the field of nutrigenomics, it was possible to elucidate how the majority of dietary fatty acids influence plasma lipid metabolism and also the genes expression involved in lipolysis and lipogenesis within hepatocytes and adipocytes. The aim of this review is to examine the relevant mechanistic aspects of dietary fatty acids related to blood lipids, adipose tissue metabolism, hepatic fat storage and inflammatory process, all of them closely related to the genesis of metabolic syndrome
机译：脂代谢异常是代谢综合征发展中的关键组成部分，代谢综合征是一种以血脂异常，胰岛素抵抗，腹部肥胖和高血压为特征的非常常见的疾病，与2型糖尿病的风险增加有关。代谢综合征的患病率与肥胖的严重程度密切相关。其生理病理学与遗传学和食物摄入习惯有关，尤其是高热量，高脂肪和高碳水化合物饮食的消费。随着营养基因组学领域科学知识的进步，有可能阐明大多数饮食脂肪酸如何影响血浆脂质代谢以及肝细胞和脂肪细胞中参与脂肪分解和脂肪生成的基因表达。这篇综述的目的是研究与血脂，脂肪组织代谢，肝脂肪储存和炎症过程有关的饮食脂肪酸的相关机理，它们均与代谢综合征的发生密切相关。

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