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首页> 外文期刊>The journals of gerontology.Series A. Biological sciences and medical sciences >Low socioeconomic status and body mass index as risk factors for inflammation in older adults: conjoint influence on C-reactive protein?
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Low socioeconomic status and body mass index as risk factors for inflammation in older adults: conjoint influence on C-reactive protein?

机译:低社会经济地位和体重指数是老年人发炎的危险因素:对C反应蛋白的共同影响?

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BACKGROUND: Low socioeconomic status and high levels of body mass are two risk factors for elevated C-reactive protein, a biomeasure signifying inflammation. Though past research identifies the additive effect of these particular risk factors, this study examines their interactive effects to uncover whether body mass index exacerbates or levels the detrimental consequences of occupying a disadvantaged social position. METHODS: This study employs a representative survey of American adults, aged 57-84 years, using self-reported and laboratory measures. Additive and multiplicative linear regression models are used to analyze logged C-reactive protein levels (mg/l) drawn from assayed blood samples. RESULTS: Significant negative interactions were observed between body mass index and two indicators of low socioeconomic status on C-reactive protein, reflecting a cross-over effect. CONCLUSIONS: The results demonstrated the importance of a multiplicative model for studying risk factor accumulation and identify low socioeconomic status as an early and primary risk factor for elevated C-reactive protein.
机译:背景:低社会经济地位和高体重水平是C反应蛋白升高的两个危险因素,C是一种指示炎症的生物措施。尽管过去的研究确定了这些特定风险因素的累加效应,但本研究还是研究了它们的相互作用,以揭示体重指数是加剧还是降低了处于不利社会地位的有害后果。方法:本研究采用自我报告和实验室测量方法,对57-84岁的美国成年人进行了代表性调查。加性和乘性线性回归模型用于分析从化验血样中得出的记录的C反应蛋白水平(mg / l)。结果:体重指数和两个低社会经济地位指标对C反应蛋白之间存在显着的负向相互作用,反映了交叉效应。结论:结果证明了乘数模型对于研究危险因素积累并确定低社会经济地位是C反应蛋白升高的早期和主要危险因素的重要性。

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