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首页> 外文期刊>The journals of gerontology.Series A. Biological sciences and medical sciences >Fatigue in a representative population of older persons and its association with functional impairment, functional limitation, and disability.
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Fatigue in a representative population of older persons and its association with functional impairment, functional limitation, and disability.

机译：有代表性的老年人口中的疲劳及其与功能障碍，功能受限和残疾的关系。

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BACKGROUND: Older persons often complain of fatigue, but the functional consequences of this symptom are unclear. The aim of the present study was to evaluate fatigue and its association with measures of physical function and disability in a representative sample of the older population. METHODS: Cross-sectional data from a population-based sample of 1,055 Italian men and women aged 65 and older were analyzed. Fatigue was defined according to two questions evaluating whether participants felt that "everything was an effort" and/or they "could not get going" on three or more days in the past week. Objective measures of physical function were handgrip strength, the Short Physical Performance Battery (SPPB), and 400-m walking speed. Disability was defined as the inability to complete the 400-m walk test and self-reported difficulty in activities of daily living (ADL) and instrumental activities of daily living (IADL). RESULTS: The prevalence of fatigue was higher in women (29%) than in men (15%). In age-adjusted analyses, fatigued men and women had weaker handgrip strength, lower SPPB score, slower walking speed, and higher mobility, ADL, and IADL disability than nonfatigued persons. Further adjustment for health behaviors, diseases, inflammatory markers, and thyroid function generally reduced the relationship between fatigue and functional outcomes, but fatigue remained significantly associated with SPPB score, walking speed, and mobility and IADL disability. CONCLUSIONS: Older persons who report fatigue had significantly poorer functional status than those who did not report this symptom. The causal link between fatigue and these outcomes should be further investigated.
机译：背景：老年人经常抱怨疲劳，但是这种症状的功能后果尚不清楚。本研究的目的是评估老年人群的代表性样本中的疲劳及其与身体功能和残疾程度的关联。方法：分析了以人口为基础的1055名65岁及以上的意大利男性和女性的抽样数据。疲劳是根据两个问题来定义的，该问题评估参与者在过去一周中的三天或更长时间里是否感到“一切都是努力”和/或“无法参加”。身体功能的客观指标是握力，短物理性能电池（SPPB）和400米步行速度。残疾被定义为无法完成400米的步行测试，并且无法自我报告日常生活活动（ADL）和仪器生活活动（IADL）的困难。结果：女性（29％）的疲劳发生率高于男性（15％）。在经过年龄调整的分析中，疲劳的男人和女人比没有疲劳的人具有较弱的握力，较低的SPPB评分，较慢的行走速度以及较高的活动能力，ADL和IADL残疾。进一步调整健康行为，疾病，炎性标志物和甲状腺功能通常可以减少疲劳与功能预后之间的关系，但是疲劳仍然与SPPB评分，步行速度，活动能力和IADL残疾显着相关。结论：报告疲劳的老年人比未报告此症状的老年人的功能状态明显较差。疲劳与这些结果之间的因果关系应进一步研究。

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