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A clinical study on the magnetic stimulation of the facial nerve.

机译:面神经磁刺激的临床研究。

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OBJECTIVES: A clinical study on the usefulness of magnetic stimulation of the facial nerve, with special attention paid to the selection of the coil shape and stimulation procedures. STUDY DESIGN: The subjects consisted of 55 patients with Bell's palsy, 1 patient with a cerebellopontine angle (CPA) tumor, 1 patient with multiple sclerosis (MS), and 30 normal subjects. Three types of coils were used in this study; a 90-mm large single coil, a 40-mm small single coil, and a 20-mm small double coil. METHODS: The compound muscle action potentials (CMAPs) and long latency response were evoked by transcranial magnetic stimulation (TMS) with a 90-mm large single coil. The 40-mm small single coil was used to test blink reflex by aiming it at the supraorbital nerve as the target site. The subcutaneous activation of the infra-auricular facial nerve was performed with the 20-mm double coil. RESULTS: The reproducible CMAP and long latency responses were obtained from normal subjects with TMS. However, responses were observed only in patients with relatively mild Bell's palsy. The magnetic stimulation-evoked responses reflected the brainstem function in the patients with a CPA tumor and MS. CONCLUSION: Although magnetic stimulation remains inferior to conventional electric stimulation in some sense and requires further study, this method is potentially useful because it can stimulate the facial nerve continuously from the cortex to the periphery and can effectively evoke responses reflecting the brainstem function.
机译:目的:对面神经进行磁刺激有用性的临床研究,尤其要注意线圈形状的选择和刺激程序。研究设计:受试者包括55例贝尔氏麻痹患者,1例小脑桥脑角(CPA)肿瘤,1例多发性硬化症(MS)和30例正常受试者。在这项研究中使用了三种类型的线圈。一个90毫米大的单线圈,一个40毫米的小单线圈和一个20毫米的小双线圈。方法:采用90毫米大的单线圈经颅磁刺激(TMS)诱发复合肌肉动作电位(CMAP)和长潜伏期反应。通过将40毫米小的单个线圈对准眼眶上神经作为目标部位来测试眨眼反射。用20毫米双线圈进行耳下面部神经的皮下激活。结果:可再现的CMAP和长潜伏期反应是从TMS的正常受试者获得的。但是,仅在贝尔轻度麻痹的患者中观察到了反应。磁刺激诱发的反应反映了CPA肿瘤和MS患者的脑干功能。结论:尽管磁刺激在某种意义上仍不如常规电刺激,尚需进一步研究,但该方法可能有用,因为它可以从皮层到周围连续刺激面神经,并且可以有效地引起反映脑干功能的反应。

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