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首页> 外文期刊>The Laryngoscope: A Medical Journal for Clinical and Research Contributions in Otolaryngology, Head and Neck Medicine and Surgery, Facial Plastic and Reconstructive Surgery .. >Impact of surveillance on survival after laryngeal cancer in the medicare population.
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Impact of surveillance on survival after laryngeal cancer in the medicare population.

机译：监测对医疗保险人群喉癌术后生存的影响。

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OBJECTIVES/HYPOTHESIS: Routine surveillance is advocated to detect recurrent disease after treatment for laryngeal cancer. This aim of this study was to determine the 1- and 5-year postrecurrence mortality for laryngeal cancers and evaluate whether more intensive surveillance improved survival. STUDY DESIGN: Retrospective cohort study. METHODS: Patients with recurrent cancers (1992-1999) were identified in a national cancer clinical database. Multivariate analysis was used to evaluate the effect of surveillance on postrecurrence survival. RESULTS: Of 2,121 recurrent cancers identified, 913 were laryngeal. Patients with laryngeal cancer recurrence had 27% (P = .001) and 22% (P = .007) better odds of 1- and 5-year survival than other sites. The 1- and 5-year postrecurrence survival rates for laryngeal cancer patients were 72.4% and 41.3%, respectively. Glottic cancer cases had the best postrecurrence life expectancy. Multivariate regression revealed that clinical surveillance intensity had no independent impact on their survival (P < .05). However, patients with recurrent glottic cancer seen in surveillance had 23% improved odds of survival (P = .037). CONCLUSIONS: More frequent surveillance visits was not associated with a survival advantage in the overall population. Patients with glottic cancer had a postrecurrence survival advantage if seen during the surveillance period. Laryngeal cancer patients had better postrecurrence survival than other head and neck sites.
机译：目的/假设：提倡常规监测以发现喉癌治疗后的复发性疾病。这项研究的目的是确定喉癌的1年和5年复发后死亡率，并评估是否加强监护能改善生存率。研究设计：回顾性队列研究。方法：在国家癌症临床数据库中鉴定出患有复发性癌症的患者（1992-1999年）。多变量分析用于评估监测对复发后生存的影响。结果：在确定的2,121例复发性癌症中，有913例是喉癌。喉癌复发患者的1年和5年生存率比其他部位高27％（P = .001）和22％（P = .007）。喉癌患者的1年和5年复发生存率分别为72.4％和41.3％。声门癌病例的复发后预期寿命最佳。多因素回归显示，临床监测强度对其生存率没有独立影响（P <.05）。但是，在监测中发现的复发性声门癌患者的生存几率提高了23％（P = .037）。结论：更频繁的监视就诊与总人口的生存优势无关。如果在监测期内发现，声门癌患者具有复发后生存优势。喉癌患者的复发后存活率高于其他头颈部部位。

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