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首页> 外文期刊>The Laryngoscope: A Medical Journal for Clinical and Research Contributions in Otolaryngology, Head and Neck Medicine and Surgery, Facial Plastic and Reconstructive Surgery .. >Acute supraglottitis in adults in Finland: review and analysis of 308 cases.
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Acute supraglottitis in adults in Finland: review and analysis of 308 cases.

机译：芬兰成人急性声门上炎：308例回顾与分析。

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OBJECTIVE: The aim of this article is to study the clinical features, management, and outcome in adult patients with acute supraglottitis. STUDY DESIGN: Retrospective review. METHODS: We searched the medical records from our database from the years 1989 to 2009 using codes of international statistical classification of diseases and related health problems for acute epiglottitis or supraglottitis. In total, 308 patients were identified. RESULTS: Incidence of acute supraglottitis increased from 1.88 (first decade) to 4.73 per 100,000 cases (second decade) (P = .05). The mean age of the patients was 49 years old with a slightly male predominance. Sore throat and odynophagia were the most common symptoms. Concomitant disease were common among the patients. Isolated inflammation of epiglottis without involvement of other supraglottic tissue was detected only in 51 patients. Intravenous cephalosporins were the most common empiric antibiotic treatment regimen. Intravenous corticosteroids were administered to half of the cases. Streptococcus was the most common organism in throat cultures. In total, 45 patients needed airway intervention. Complications were rare and mortality was 0.6% in our series. CONCLUSIONS: Acute supraglottitis in adults seems to be a different entity than epiglottitis in children, and inflammation does not usually exclusively involve the epiglottis. Early diagnosis seems to decrease the need for airway intervention and to permit the successful treatment of the patient with intravenous antibiotics and corticosteroids. Streptococcus appears as the dominant causative microorganism. However systemic diseases and other local infections that compromise the regional supraglottic immunity may increase the risk for acute supraglottitis.
机译：目的：本文旨在研究成人急性声门上炎的临床特征，治疗方法和转归。研究设计：回顾性审查。方法：我们从1989年至2009年使用国际统计分类法对急性会厌炎或声门上炎和相关健康问题进行分类，从我们的数据库中检索病历。总共确定了308名患者。结果：急性声门上炎的发病率从每十年100,000例中的1.88（第二个十年）增加到4.73（P = 0.05）。患者的平均年龄为49岁，男性稍占优势。喉咙痛和吞咽痛是最常见的症状。伴随疾病在患者中很常见。仅51例患者中检出了会厌的孤立炎症，而没有其他声门上组织的累及。静脉注射头孢菌素是最常见的经验性抗生素治疗方案。一半病例使用了静脉注射皮质类固醇激素。链球菌是咽喉培养物中最常见的生物。总共有45位患者需要气道干预。在我们的系列中，并发症很少见，死亡率为0.6％。结论：成人急性声门上炎似乎不同于儿童会厌炎，而且炎症通常不仅仅涉及会厌。早期诊断似乎减少了对气道干预的需求，并允许静脉内使用抗生素和糖皮质激素成功治疗患者。链球菌是主要的致病微生物。但是，损害区域声门上免疫力的全身性疾病和其他局部感染可能会增加发生急性声门上炎的风险。

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