...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The American Journal of Cardiology >Efficacy of the CHADS2 scoring system to assess left atrial thrombogenic milieu risk before cardioversion of non-valvular atrial fibrillation
【24h】

Efficacy of the CHADS2 scoring system to assess left atrial thrombogenic milieu risk before cardioversion of non-valvular atrial fibrillation

机译：CHADS2评分系统评估非瓣膜性房颤的心脏复律前评估左心房血栓形成环境风险的功效

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The CHADS2 scoring system was found to be a good predictor for risk stratification of stroke in patients with atrial fibrillation. The effectiveness of this scoring system in assessing thrombogenic milieu before direct-current cardioversion has not yet fully been established on a large scale. In this study, data from 2,369 consecutive patients in whom transesophageal echocardiography was performed for screening before direct-current cardioversion from 1999 to 2008 were analyzed. Left atrial (LA) or LA appendage (LAA) thrombogenic milieu (spontaneous echo contrast, sludge, and thrombus) was investigated. The results were correlated with CHADS 2 score findings. The mean age was 66 ± 13 years, and the ratio of men to women was 2.2:1. CHADS2 scores of 0, 1, 2, 3, 4, 5 and 6 were present in 11%, 25%, 30%, 22%, 8%, 3%, and 1% of the studies, respectively. The prevalence of LA or LAA sludge or thrombus increased with increasing CHADS2 scores (2.3%, 7%, 8.5%, 9.9%, 12.3%, and 14.1% for scores of 0, 1, 2, 3, 4, and 5 or 6, respectively, p = 0.01). In a multivariate model, an ejection fraction ≤20% was the best predictor of LA or LAA sludge or thrombus (odds ratio 2.99, p 0.001). In conclusion, transesophageal echocardiographic markers of thrombogenic milieu were highly correlated with increasing CHADS2 scores in patients who underwent transesophageal echocardiography-guided cardioversion. Giving more value to echocardiographic findings, such as the left ventricular ejection fraction, and its different levels (especially an ejection fraction ≤20%) might improve the precision of the CHADS2 scoring scheme to predict thrombogenic milieu in the left atrium or LAA as a surrogate to cardioembolic risk in patients with atrial fibrillation.
机译：发现CHADS2评分系统可以很好地预测房颤患者中风的危险分层。在直流电复律之前，该评分系统在评估血栓形成环境方面的有效性尚未完全建立。在这项研究中，分析了1999年至2008年连续2369例接受直流电复律前经食道超声心动图检查的患者的数据。研究了左心房（LA）或LA附肢（LAA）的血栓形成环境（自发回声对比，淤泥和血栓）。结果与CHADS 2评分结果相关。平均年龄为66±13岁，男女比例为2.2：1。 CHADS2分数分别为11％，25％，30％，22％，8％，3％和1％，分别为0、1、2、3、4、5和6。 LA或LAA污泥或血栓的患病率随着CHADS2分数的增加而增加（分数分别为0、1、2、3、4、5或6的2.3％，7％，8.5％，9.9％，12.3％和14.1％ ，分别为p = 0.01）。在多变量模型中，射血分数≤20％是LA或LAA污泥或血栓的最佳预测指标（几率2.99，p <0.001）。总之，在经食道超声心动图指导的心脏复律患者中，经血栓形成的环境的食管超声心动图标记与CHADS2评分的升高高度相关。赋予超声心动图检查结果更多的价值，例如左心室射血分数及其不同水平（尤其是射血分数≤20％），可能会改善CHADS2评分方案预测左心房或LAA的血栓形成环境的准确性。降低房颤患者的心脏栓塞风险。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号