Characteristics and outcomes of acute otitis media in children carrying streptococcus pneumoniae or haemophilus influenzae in their nasopharynx as a single otopathogen after introduction of the heptavalent pneumococcal conjugate vaccine

CaeymaexL.; VaronE.; LevyC.; BéchetS.; DerkxV.; DesvignesV.; DoitC.; CohenR.

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Characteristics and outcomes of acute otitis media in children carrying streptococcus pneumoniae or haemophilus influenzae in their nasopharynx as a single otopathogen after introduction of the heptavalent pneumococcal conjugate vaccine

机译：引入七价肺炎球菌结合疫苗后，鼻咽中携带链球菌肺炎或流感嗜血杆菌作为单一致病菌的儿童急性中耳炎的特征和转归

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After PCV7 implementation, clinical characteristics were investigated in 832 young children with acute otitis media, carrying a single S. pneumoniae or H. influenzae in their nasopharynx. As compared with H. influenzae, S. pneumoniae-associated acute otitis media was less frequently associated with treatment failure (odds ratio = 0.5; 95% confidence interval: 0.36-0.83) and recurrence (odds ratio = 0.4; 95% confidence interval: 0.22-0.75). Post-PCV7 serotype replacement seemed not to affect the acute otitis media characteristics in these children.

机译：实施PCV7后，对832名患有急性中耳炎的儿童进行了临床特征调查，这些儿童的鼻咽中携带单个肺炎链球菌或流感嗜血杆菌。与流感嗜血杆菌相比，肺炎链球菌相关的急性中耳炎与治疗失败（几率= 0.5; 95％置信区间：0.36-0.83）和复发（几率= 0.4; 95％置信区间： 0.22-0.75）。 PCV7后血清型替代似乎不影响这些儿童的急性中耳炎特征。

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《The Pediatric infectious disease journal》 |2014年第5期|共4页
作者
CaeymaexL.; VaronE.; LevyC.; BéchetS.; DerkxV.; DesvignesV.; DoitC.; CohenR.;
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正文语种 eng
中图分类儿科学;
关键词
acute otitis media; Haemophilus influenzae; PCV7; Streptococcus pneumoniae;

机译：急性中耳炎;流感嗜血杆菌;PCV7;肺炎链球菌;

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1. Characteristics and outcomes of acute otitis media in children carrying streptococcus pneumoniae or haemophilus influenzae in their nasopharynx as a single otopathogen after introduction of the heptavalent pneumococcal conjugate vaccine [J] . CaeymaexL., VaronE., LevyC., The Pediatric infectious disease journal . 2014,第5期

机译：引入七价肺炎球菌结合疫苗后，鼻咽中携带链球菌肺炎或流感嗜血杆菌作为单一致病菌的儿童急性中耳炎的特征和转归
2. Microbiological characterization of Streptococcus pneumoniae and non-typeable Haemophilus influenzae isolates as primary causes of acute otitis media in Bulgarian children before the introduction of conjugate vaccines [J] . Lena P Setchanova, Tomislav Kostyanev, Alexandra B Alexandrova, Annals of Clinical Microbiology and Antimicrobials . 2013,第1期

机译：引入结合疫苗前，保加利亚儿童肺炎链球菌和不可分型流感嗜血杆菌分离株的微生物学特征是急性中耳炎的主要原因
3. Biofilm production by Haemophilus influenzae and Streptococcus pneumoniae isolated from the nasopharynx of children with acute otitis media [J] . Quentin Vermee, Robert Cohen, Constantin Hays, BMC Infectious Diseases . 2019,第1期

机译：生物膜通过嗜血杆菌和肺炎链球菌的生物膜生产与急性中耳炎的儿童鼻咽分离出来
4. Microbiology of acute otitis media with perforation (AOMwiP) in Aboriginal children living in remote communities-monitoring the impact of 7-valent pneumococcal conjugate vaccine (7vPCV) [C] . Amanda Leach, Grant MacKenzie, Kim Hare, Lancefield International Symposium on Streptococci and Streptococcal Diseases . 2006

机译：具有穿孔（Aomwip）的急性中耳炎的微生物学，在偏远社区生活在偏远社区中的土着儿童 - 监测7价肺炎球菌缀合物疫苗的影响（7VPCV）
5. Protein Vaccines Against Acute Otitis Media Caused by Nontypeable Haemophilus influenzae in a Murine Model [D] . Zavorin, Mark. 2018

机译：蛋白质疫苗针对鼠模型中的不可迁移血液血液嗜血杆菌引起的急性中耳炎
6. Trends in antibiotic resistance of Streptococcus pneumoniae and Haemophilus influenzae isolated from nasopharyngeal flora in children with acute otitis media in France before and after 13 valent pneumococcal conjugate vaccine introduction [O] . François Angoulvant, Robert Cohen, Catherine Doit, 2015

机译：从法国鼻咽菌群中分离出的肺炎链球菌和流感嗜血杆菌对13价肺炎球菌结合疫苗接种前后儿童急性中耳炎的耐药性趋势
7. Microbiological characterization of Streptococcus pneumoniae and non-typeable Haemophilus influenzae isolates as primary causes of acute otitis media in Bulgarian children before the introduction of conjugate vaccines [O] . Lena P Setchanova, Tomislav Kostyanev, Alexandra B Alexandrova, 2013

机译：引入结合疫苗前，保加利亚儿童肺炎链球菌和不可分型流感嗜血杆菌分离株的微生物学特征是急性中耳炎的主要原因

Characteristics and outcomes of acute otitis media in children carrying streptococcus pneumoniae or haemophilus influenzae in their nasopharynx as a single otopathogen after introduction of the heptavalent pneumococcal conjugate vaccine

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