The role of obesity in gastrointestinal cancer: Evidence and opinion

DonohoeC.L.; OFarrellN.J.; DoyleS.L.; ReynoldsJ.V.

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The role of obesity in gastrointestinal cancer: Evidence and opinion

机译：肥胖在胃肠道癌症中的作用：证据和见解

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There is increasing recognition of the impact of being overweight and obese on the development of cancers at diverse sites including the gastrointestinal tract. Large epidemiological studies indicate that up to 14% of tumours may be related to obesity. Pathophysiological mechanisms underpinning this association are not well understood and so are discussed in this review.

机译：人们越来越认识到，超重和肥胖对包括胃肠道在内的不同部位的癌症的发展具有影响。大型流行病学研究表明，多达14％的肿瘤可能与肥胖有关。尚不清楚这种关联的病理生理机制，因此在本综述中进行了讨论。

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《Therapeutic advances in gastroenterology.》 |2014年第1期|共13页
作者
DonohoeC.L.; OFarrellN.J.; DoyleS.L.; ReynoldsJ.V.;
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正文语种 eng
中图分类消化系及腹部疾病;
关键词
adipose tissue; carcinogenesis; inflammation; signalling pathways; visceral adiposity;

机译：脂肪组织;致癌作用;炎症;信号通路;内脏脂肪;

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1. The role of obesity in gastrointestinal cancer: Evidence and opinion [J] . DonohoeC.L., OFarrellN.J., DoyleS.L., Therapeutic advances in gastroenterology. . 2014,第1期

机译：肥胖在胃肠道癌症中的作用：证据和见解
2. The role of obesity in gastrointestinal cancer: evidence and opinion [J] . Claire L. Donohoe, Naoimh J. O’Farrell, Suzanne L. Doyle, Therapeutic advances in gastroenterology. . 2014,第1期

机译：肥胖在胃肠道癌症中的作用：证据和见解
3. Adiponectin is not effective against AOM-induced colon cancer but more evidence is required for its role in obesity-associated colon cancer: comment on the study by Ealey and Archer (2009). [J] . Chen J, Huang XF International Journal of Cancer =: Journal International du Cancer . 2009,第10期

机译：脂联素不能有效对抗AOM引起的结肠癌，但需要更多的证据证明其在肥胖相关的结肠癌中的作用：Ealey and Archer（2009）对这项研究的评论。
4. Unraveling the Obesity and Breast Cancer Links: A Role for Cancer-Associated Adipocytes? [C] . Beatrice Dirat, Ludivine Bochet, Ghislaine Escourrou, ESPE Advanced Seminar in Developmental Endocrinology . 2010

机译：解开肥胖症和乳腺癌链接：癌症相关的脂肪细胞的作用？
5. The Role of Microbiota in Gastrointestinal Cancers [D] . Smietalo, Norbert 2019

机译：微生物群在胃肠道癌症中的作用
6. The role of obesity in gastrointestinal cancer: evidence and opinion [O] . Claire L. Donohoe, Naoimh J. O’Farrell, Suzanne L. Doyle, 2014

机译：肥胖在胃肠道癌症中的作用：证据和见解
7. The Role of Sarcopenic Obesity in Cancer and Cardiovascular Disease: A Synthesis of the Evidence on Pathophysiological Aspects and Clinical Implications [O] . Erika Aparecida Silveira, Rômulo Roosevelt da Silva Filho, Maria Claudia Bernardes Spexoto, 2021

机译：嗜睡肥胖在癌症和心血管疾病中的作用：对病理生理方面的综合证据和临床意义
8. Investigate the Role of Obesity in Ovarian Cancer Initiation and Progression. [R] . Guarente, L. P., Chalkiadaki, A. 2017

机译：调查肥胖在卵巢癌发病和进展中的作用。

The role of obesity in gastrointestinal cancer: Evidence and opinion

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