...
【24h】

Plant ARGONAUTES.

机译:植物花粉。

获取原文
获取原文并翻译 | 示例
           

摘要

ARGONAUTE (AGO) proteins are integral players in all known small RNA-directed regulatory pathways. Eukaryotes produce numerous types of small RNAs, such as microRNAs (miRNA), small interfering RNAs (siRNA), PIWI-interacting RNAs (piRNAs), scanRNAs and 21U-RNAs, and these RNA species associate with different types of AGO family members, such as AGO, PIWI and group 3 proteins. Small RNA-guided AGO proteins regulate gene expression at various levels, including internal genomic DNA sequence elimination (in ciliates), translational repression (animals), and RNA cleavage (all eukaryotes), which in some cases is followed by DNA methylation and chromatin remodeling. The plant model species Arabidopsis contains ten AGO proteins belonging to three phylogenetic clades. This review covers our current knowledge of plant AGO functions during miRNA- and siRNA-mediated regulation of development and stress responses, siRNA-mediated antiviral immune response, and siRNA-mediated regulation of chromatin structure and transposons.
机译:ARGONAUTE(AGO)蛋白在所有已知的小RNA定向调控途径中都是不可或缺的角色。真核生物产生多种类型的小RNA,例如microRNA(miRNA),小干扰RNA(siRNA),PIWI相互作用RNA(piRNA),scanRNA和21U-RNA,这些RNA种类与不同类型的AGO家族成员相关,例如作为AGO,PIWI和第3组蛋白。小型RNA引导的AGO蛋白在各个水平上调节基因表达,包括内部基因组DNA序列消除(纤毛),翻译抑制(动物)和RNA裂解(所有真核生物),在某些情况下,随后是DNA甲基化和染色质重塑。植物模型物种拟南芥包含十个属于三个系统发育进化枝的AGO蛋白。这篇综述涵盖了我们目前对植物AGO在miRNA和siRNA介导的发育和应激反应调控,siRNA介导的抗病毒免疫反应以及siRNA介导的染色质结构和转座子调控过程​​中功能的认识。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号