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Transcytosis shuts the door for an unwanted guest

机译:转胞吞症关闭了一个不需要的客人的门

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Penetration resistance is a well-described plant defense process, in which SOLUBLE N-ETHYLMALEIMIDE-SENSITIVE-FACTOR ATTACHMENT RECEPTOR (SNARE) proteins have essential roles in membrane fusion processes. Strong focal accumulation of these proteins at the site of attack by powdery mildew fungi has been considered important for their function. However, recent insight indicates that transcytosis, leading to the formation of exosomes, has an important role in this defense and, furthermore, that strong accumulation of these SNARE proteins with the exosomes is biologically irrelevant. These findings alter the established function of SNAREs in penetration resistance; therefore, in this opinion, we propose that PEN1 and its SNARE partners function on an endosome in their control of penetration resistance.
机译:防渗透性是众所周知的植物防御过程,其中可溶性N-乙基丙二酰亚胺-敏感因子附着受体(SNARE)蛋白在膜融合过程中具有重要作用。这些蛋白质在由白粉病真菌侵袭的部位上强烈的焦点积累被认为对其功能很重要。但是,最近的见解表明,导致胞外体形成的转胞吞作用在这种防御中具有重要作用,此外,这些SNARE蛋白与胞外体的强积累在生物学上无关紧要。这些发现改变了SNARE在抗穿透性方面的既定功能。因此,根据这种观点,我们建议PEN1及其SNARE伙伴在控制渗透阻力的过程中对内体起作用。

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