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首页> 外文期刊>Tumori. >Quality control of the autopap screening system employed as a primary screening device: rapid review of smears coded as no further review.
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Quality control of the autopap screening system employed as a primary screening device: rapid review of smears coded as no further review.

机译：作为主要筛查设备的autopap筛查系统的质量控制：对涂片的快速检查已编码为无需进一步检查。

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摘要

AIMS AND BACKGROUND: Automated reading of smears is increasingly used in cervical screening, and quality control procedures to check its performance are required. The aim of the present study was to evaluate the usefulness of rapid review of all smears coded as "no further review" (NFR) by the AutoPap system as a quality control procedure. METHODS: From 2002-2005, 153,269 smears were processed by AutoPap at the Centro per lo Studio e la Prevenzione Oncologica of Florence, Italy, and 24,503 (15.9%) were coded as NFR. All NFR smears underwent immediate rapid review by expert readers. RESULTS: Sixty-five of 118 NFR cases reviewed as ASCUS-R complied to recommended 6 months cytology, and 25 of 30 NFR cases reviewed as ASCUS-SIL or more severe accepted immediate colposcopy. As a result of such assessment, one single case of microinvasive carcinoma was detected in a woman aged 34 years: NFR smear had been reviewed as AGCUS, was followed by repeat AGCUS cytology and repeat negative colposcopy, and finally underwent conization. CONCLUSIONS: NFR report at AutoPap was associated with an extremely high negative predictive value, which might suggest using AutoPap as a primary screening tool, with NFR report prompting a "return to screening" recommendation. Rapid review of NFR smears is not recommended as a quality control measure for the negligible yield of high-grade lesions detected.
机译：目的和背景：在宫颈筛查中越来越多地使用自动读取涂片，并且需要质量控制程序来检查其性能。本研究的目的是评估由AutoPap系统快速检查所有编码为“无进一步检查”（NFR）的涂片作为质量控制程序的有用性。方法：从2002年至2005年，AutoPap在意大利佛罗伦萨的Studio e la Prevenzione Oncologica中心处理了153,269涂片，并将24,503（15.9％）编码为NFR。所有NFR涂片均由专家读者立即进行了快速审查。结果：118例经NSC检查的NFR病例中有65例符合推荐的6个月细胞学检查，而30例经NSC SIL或更严重检查的NFR病例中有25例接受了立即阴道镜检查。评估的结果是，在一名34岁的女性中发现了1例微浸润癌：NFR涂片检查为AGCUS，随后进行了重复的AGCUS细胞学检查和重复的阴性阴道镜检查，最后进行了锥切术。结论：AutoPap的NFR报告与极高的阴性预测值相关，这可能表明使用AutoPap作为主要的筛查工具，NFR报告提示“返回筛查”建议。不建议对NFR涂片进行快速检查以作为检测到的高级别病变的可忽略的质量控制措施。

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