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Chemosensory signaling systems that control bacterial survival

机译:控制细菌存活的化学感应信号系统

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Recent studies have revealed that several Gram-negative species utilize variations of the well-known chemotaxis signaling cascade to switch lifestyles in order to survive environmental stress. The two survival strategies covered in this review are the development of dormant cyst cells and biofilm formation. Each of these structures involves exopolysaccharide-mediated cell cell interactions, which result in multicellular communities that confer resistance to stress conditions such as desiccation and antibiotics. This review is centered on recent advances in the understanding of phosphate flow and novel output signals in chemosensory signaling pathways that are involved in cyst formation and biofilms
机译:最近的研究表明,一些革兰氏阴性物种利用众所周知的趋化性信号级联的变异来改变生活方式,以度过环境压力。这篇综述涵盖的两种生存策略是休眠性囊肿细胞的发展和生物膜的形成。这些结构中的每一个都涉及胞外多糖介导的细胞之间的相互作用,从而导致多细胞群落对干旱和抗生素等胁迫条件产生抗性。这篇综述的重点是在理解磷酸盐流和化学传感信号通路中涉及囊肿形成和生物膜的新型输出信号方面的最新进展。

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