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A nutritive view on the host–pathogen interplay

机译:宿主与病原体相互作用的营养观点

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The interaction between pathogenic microbes and their host is determined by survival strategies on both sides, including competition for essential nutrients. During evolution, pathogenic microbes developed ways to access certain nutrients from the host, which, by contrast, can be exploited by the host for defence by restricting the availability of these nutrients. In this article, we review ecological aspects of the host–pathogen relationship and describe examples for competitive nutrient usage. We also discuss the beneficial probiotic microbes of the mammalian gut, which influence their environment including inflammatory host responses, and how they might be supported by prebiotic diets.
机译:病原微生物与其宿主之间的相互作用取决于双方的生存策略,包括对必需营养素的竞争。在进化过程中,病原微生物开发了从宿主获取某些养分的方法,相比之下,宿主可以通过限制这些养分的利用来利用这些养分进行防御。在本文中,我们回顾了宿主与病原体关系的生态方面,并举例说明了竞争性养分的使用。我们还讨论了有益于哺乳动物肠道的益生菌微生物,它们会影响其环境,包括炎症宿主反应,以及益生元饮食如何支持它们。

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