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Nasopharyngeal bacterial colonisation in HIV-positive children in Cambodia

机译:柬埔寨艾滋病毒呈阳性儿童的鼻咽细菌定植

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摘要

Objective: To determine patterns of nasopharyngeal colonisation in HIV-positive children. Methods: Nasopharyngeal, nasal and ear swabs were prospectively taken from all children living in two paediatric nursing homes for HIV-positive orphans in Cambodia from 2004 to 2011. Results: A total of 882 swabs were taken, of which 586 tested positive for bacteria. Staphylococcus aureus was the most frequently isolated species (178 isolates; 30.4%) followed by Streptococcus pneumoniae (103 isolates; 17.6%) and Klebsiella pneumoniae (99 isolates; 16.9%). The rate of S. pneumoniae decreased in 2009 when a vaccination programme was introduced. Conclusions: The respiratory tract of HIV-positive children receiving highly active antiretroviral therapy is commonly colonised by S. aureus and S. pneumoniae, while other species normally found in the respiratory tract, such as Moraxella catarrhalis, are far less frequent.
机译:目的:确定HIV阳性儿童的鼻咽定植模式。方法:前瞻性地从2004年至2011年在柬埔寨两个艾滋病毒阳性孤儿的儿科护理院中的儿童中抽取鼻咽,鼻拭子和耳拭子。结果:共抽取882个拭子,其中586个细菌检测为阳性。金黄色葡萄球菌是最常见的物种(178株; 30.4%),其次是肺炎链球菌(103株; 17.6%)和肺炎克雷伯菌(99株; 16.9%)。 2009年,在实施疫苗接种计划后,肺炎链球菌的发病率有所下降。结论:接受高活性抗逆转录病毒治疗的HIV阳性儿童的呼吸道通常被金黄色葡萄球菌和肺炎链球菌所定殖,而通常在呼吸道中发现的其他物种(例如卡他莫拉菌)则要少得多。

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