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首页> 外文期刊>Vascular and endovascular surgery >Hypercoagulable state due to alcohol-paracetamol syndrome producing acute limb ischemia.
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Hypercoagulable state due to alcohol-paracetamol syndrome producing acute limb ischemia.

机译:酒精-扑热息痛综合征引起的高凝状态导致急性肢体缺血。

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The authors describe a man with alcohol-paracetamol syndrome and hepatic failure who presented with acute arterial thrombosis of the left limb. The patient has jaundice, increased serum transaminase levels, and significant coagulopathy, with elevated international normalized ratio and prolonged prothrombin time. A transient hypercoagulable state due to liver failure is documented, characterized by acquired deficiencies of antithrombin III, protein C, and protein S. Laboratory and molecular testing for inherited hypercoagulable disorders during the follow-up period is positive for increased levels of factor VIII. The patient undergoes successful thrombectomy and receives intensive symptomatic and causal treatment, resulting in complete recovery. The patient is discharged 20 days after admission on a regimen of acenocoumarol.
机译:作者描述了一个患有酒精-扑热息痛综合征和肝功能衰竭的男子,其左肢急性动脉血栓形成。该患者患有黄疸,血清转氨酶水平升高和明显的凝血病,国际标准化比率升高且凝血酶原时间延长。记录到由于肝功能衰竭导致的短暂高凝状态,其特征为获得性抗凝血酶III,蛋白C和蛋白S缺乏。在随访期间,实验室和分子检测对遗传性高凝疾病的检测对VIII因子水平升高是阳性的。患者成功进行了血栓切除术,并接受了严格的对症和因果治疗,从而完全康复。患者在入院后20天接受乙酰香豆酚治疗。

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