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首页> 外文期刊>Veterinary Dermatology >Localized cowpox infection in a 5-month-old Rottweiler.
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Localized cowpox infection in a 5-month-old Rottweiler.

机译：5个月大的罗威纳犬中的局部牛痘感染。

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Cowpox virus (CPXV) infections are a sporadic cause of localized or disseminated skin disease in domestic animals and humans in Europe. Rodents are considered the primary reservoir host for CPXV. Cats can become infected by close contact with rodents and are the most important source of human infections. Recently, public awareness has also been drawn to CPXV infections by an outbreak of rat to human infections in central Europe. In dogs, CPXV infections are rare. Here we report a case of a 5-month-old Rottweiler with a focal nodule on the muzzle. The lesion was fully excised, and recovery was uneventful. The preliminary diagnosis of a CPXV infection was established by the characteristic inclusion bodies on histopathological examination. The diagnosis was confirmed by electron microscopy and polymerase chain reaction (PCR). Sequencing of the PCR product led to a 231 bp sequence of the orthopoxvirus HA gene that was identical to a CPXV strain previously isolated from a cat. This is the third documented case of a canine CPXV infection.Digital Object Identifier http://dx.doi.org/10.1111/j.1365-3164.2010.00923.x
机译：牛痘病毒（CPXV）感染是欧洲家畜和人类局部或散布性皮肤病的偶发原因。啮齿动物被认为是CPXV的主要宿主。猫与啮齿动物紧密接触会被感染，是人类感染的最重要来源。最近，在中欧爆发了人类感染鼠疫的事件，也引起了公众对CPXV感染的认识。在狗中，CPXV感染很少见。在这里，我们报告了一例5个月大的罗威纳犬，枪口上有一个小结节。病变完全切除，恢复平稳。 CPXV感染的初步诊断是通过组织病理学检查中的特征性包涵体建立的。通过电子显微镜和聚合酶链反应（PCR）确诊。 PCR产物的测序产生正痘病毒 HA 基因的231bp序列，该序列与先前从猫中分离出的CPXV毒株相同。这是第三例犬CPXV感染案例。数字对象标识符http://dx.doi.org/10.1111/j.1365-3164.2010.00923.x

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