The hybridization between peptide nucleic acid containing azobenzene and DNA labeled nanoparticle on chip surfaces studied by atomic force microscopy

Li JinDu; Chen Miao; Zhang HaoBo; Liu Sheng; Liu JianXi

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The hybridization between peptide nucleic acid containing azobenzene and DNA labeled nanoparticle on chip surfaces studied by atomic force microscopy

机译：原子力显微镜研究含偶氮苯的肽核酸与DNA标记的纳米粒子在芯片表面的杂交

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Peptide nucleic acid containing azobenzene (N-PNA) was covalently bound on chip surfaces. Complementary DNA probes labeled by gold nanoparticles hybridizated with PNA on chip surfaces. The hybridization was successfully detected with AFM by the microscopy mothed. The influences of the position and the cis-trans isomerization of azobenzene unit on hybridization were investigated with AFM.

机译：含有偶氮苯（N-PNA）的肽核酸共价结合在芯片表面。由金纳米颗粒标记的互补DNA探针与芯片表面上的PNA杂交。通过显微镜法成功地用AFM检测了杂交。利用原子力显微镜研究了偶氮苯单元的位置和顺反异构化对杂交的影响。

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《Chinese science bulletin》 |2008年第19期|共4页
作者
Li JinDu; Chen Miao; Zhang HaoBo; Liu Sheng; Liu JianXi;
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正文语种 eng
中图分类自然科学现状及发展;
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Methods and Techniques; Biochemistry and Molecular Biophysics;

机译：方法与技术;生物化学与分子生物物理学;

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专利

1. The hybridization between peptide nucleic acid containing azobenzene and DNA labeled nanoparticle on chip surfaces studied by atomic force microscopy [J] . Li JinDu, Chen Miao, Zhang HaoBo, Chinese science bulletin . 2008,第19期

机译：原子力显微镜研究含偶氮苯的肽核酸与DNA标记的纳米粒子在芯片表面的杂交
2. Fischer carbene mediated covalent grafting of a peptide nucleic acid on gold surfaces and IR optical detection of DNA hybridization with a transition metalcarbonyl label [J] . Srivastava Pratima, Ghasemi Mahsa, Ray Namrata, Applied Surface Science . 2016,第nova1期

机译：费歇尔卡宾介导的金表面肽核酸的共价接枝和红外金属过渡金属羰基标记的光学杂交检测
3. Label-Free Detection of Peptide Nucleic Acid-DNA Hybridization Using Localized Surface Plasmon Resonance Based Optical Biosensor [J] . Tatsuro Endo, Kagan Kerman, Naoki Nagatani, Analytical chemistry . 2005,第21期

机译：基于局部表面等离振子共振的光学生物传感器的肽核酸-DNA杂交的无标记检测。
4. Localized surface plasmon resonance based label-free optical biosensor for monitoring peptide nucleic acid-DNA hybridization [C] . Endo, T., Kerman, . 2005

机译：基于局部表面等离子体共振的无标记光学生物传感器，用于监测肽核酸-DNA杂交
5. Synthetic studies on peptide nucleic acids: 1. Toward a circular bis-peptide nucleic acid. 2. Sequence and linker effects in bis-PNA hybridization to DNA. [D] . Tse, Joseph. 2004

机译：肽核酸的合成研究：1.形成环状双肽核酸。 2. bis-PNA与DNA杂交中的序列和接头效应。
6. DNA probes on chip surfaces studied by scanning force microscopy using specific binding of colloidal gold [O] . Robert Möller, Andrea Csáki, J. Michael Köhler, 2000

机译：使用胶体金的特异性结合通过扫描力显微镜研究芯片表面上的DNA探针
7. The hybridization between peptide nucleic acid containing azobenzene and DNA labeled nanoparticle on chip surfaces studied by atomic force microscopy [O] . JinDu Li, Miao Chen, HaoBo Zhang, 2008

机译：用原子力显微镜研究的偶氮苯和DNA标记纳米粒子的肽核酸之间的杂交
8. In Vitro Assessment of a Peptide Nucleic Acid (PNA) - Peptide Conjugate Labeled With an Auger-Emitting Radionuclide for Prostate Cell Killing [R] . Wilbur, S. D. 2005

机译：体外评估肽核酸（pNa） - 用俄歇发射放射性核素标记的肽缀合物用于前列腺细胞杀伤

The hybridization between peptide nucleic acid containing azobenzene and DNA labeled nanoparticle on chip surfaces studied by atomic force microscopy

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