• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Chemotherapy: International Journal of Experimental and Clinical Chemotherapy >Prospective randomized study of antibiotic prophylaxis for nonlaparotomy surgery in benign conditions.
【24h】

Prospective randomized study of antibiotic prophylaxis for nonlaparotomy surgery in benign conditions.

机译：良性条件下非开腹手术的抗生素预防性前瞻性随机研究。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

BACKGROUND: Although postoperative infections continue to be a major problem in gynecologic surgery, there is still no consensus on the efficacy of antibiotic prophylaxis. METHODS: This prospective randomized trial was conducted to investigate the prevention of major operating site infections after nonlaparotomy surgery, with treatment regimens as follows: the first group of patients received 2 g of intravenous cefotiam dihydrochloride (CTM) on the induction of anesthesia, while the second group received 100 mg of oral cefpodoxime proxetil (CPDX- PR) twice daily, from day 0 to day 2. RESULTS: Nineteen of the 207 patients enrolled developed postoperative infections diagnosed by our simple criteria for postoperative infection. The frequency of febrile morbidity was not significantly less in patients who received CTM (9 cases; 8.6%) as compared with those in the CPDX-PR group (10 cases; 9.8%) (p = 0.56). CONCLUSION: The administration of oral CPDX-PR (100 mg, twice daily, for 3 days) appears to be a safe, cost-saving, convenient prophylaxis which reduces overall expense. Copyright 2000 S. Karger AG, Basel.
机译：背景：尽管术后感染仍然是妇科手术中的主要问题，但关于抗生素预防的疗效仍未达成共识。方法：这项前瞻性随机试验旨在研究非开腹手术后主要手术部位感染的预防，其治疗方案如下：第一组患者在麻醉诱导下接受了2 g盐酸头孢替安静脉注射盐酸（CTM），而第二组从第0天到第2天每天两次接受100 mg口服头孢泊肟酯（CPDX-PR）。结果：207例患者中有19例根据我们的术后感染简单标准诊断为术后感染。与CPDX-PR组（10例; 9.8％）相比，接受CTM的患者（9例; 8.6％）的高热发病率没有显着降低（p = 0.56）。结论：口服CPDX-PR（100 mg，每天两次，连续3天）似乎是一种安全，节约，方便的预防措施，可降低总费用。版权所有2000 S. Karger AG，巴塞尔。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号