IRF5, PTPN22, CD28, IL2RA, KIF5A, BLK and TNFAIP3 genes polymorphisms and lupus susceptibility in a cohort from the Egypt Delta; relation to other ethnic groups

Elghzaly Ashraf A.; Metwally Shereen S.; El-Chennawi Farha A.; Elgayaar Maha A.; Mosaad Youssef M.; El-Toraby Ehab E.; Hegab Mohsen M.; Ibrahim Saleh M.

首页> 外文期刊>Human Immunology: Official Journal of the American Society for Histocompatibility and Immunogenetics >IRF5, PTPN22, CD28, IL2RA, KIF5A, BLK and TNFAIP3 genes polymorphisms and lupus susceptibility in a cohort from the Egypt Delta; relation to other ethnic groups

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IRF5, PTPN22, CD28, IL2RA, KIF5A, BLK and TNFAIP3 genes polymorphisms and lupus susceptibility in a cohort from the Egypt Delta; relation to other ethnic groups

机译：埃及三角洲人群的IRF5，PTPN22，CD28，IL2RA，KIF5A，BLK和TNFAIP3基因多态性和狼疮易感性;与其他种族的关系

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Objective: To replicate a single nucleotide polymorphism (SNP) of known genes for lupus (IRF5 rs10488631, PTPN22 rs2476601, BLK rs2736340 and TNFAIP3 rs5029939) and other autoimmune diseases (CD28 rs1980422, IL2R4 rs2104286 and KIF5A rs1678542) on a newly studied Egyptian cohort to investigate the genetic disparity with different studied ethnic groups in relation to lupus susceptibility.

机译：目的：在一个新研究的狼疮（IRF5 rs10488631，PTPN22 rs2476601，BLK rs2736340和TNFAIP3 rs5029939）和其他自身免疫性疾病（CD28 rs1980422，IL2R4 rs2104286和KIF5A rs1678542）上复制已知基因的单核苷酸多态性（SNP）调查与狼疮易感性有关的不同研究的种族的遗传差异。

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《Human Immunology: Official Journal of the American Society for Histocompatibility and Immunogenetics》 |2015年第7期|共7页
作者
Elghzaly Ashraf A.; Metwally Shereen S.; El-Chennawi Farha A.; Elgayaar Maha A.; Mosaad Youssef M.; El-Toraby Ehab E.; Hegab Mohsen M.; Ibrahim Saleh M.;
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正文语种 eng
中图分类医学免疫学;
关键词
Lupus; Genetics; Egyptians; Association; Ethnicity;

机译：狼疮;遗传学;埃及人;协会;民族;

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1. IRF5, PTPN22, CD28, IL2RA, KIF5A, BLK and TNFAIP3 genes polymorphisms and lupus susceptibility in a cohort from the Egypt Delta; relation to other ethnic groups [J] . Elghzaly Ashraf A., Metwally Shereen S., El-Chennawi Farha A., Human Immunology: Official Journal of the American Society for Histocompatibility and Immunogenetics . 2015,第7期

机译：埃及三角洲人群的IRF5，PTPN22，CD28，IL2RA，KIF5A，BLK和TNFAIP3基因多态性和狼疮易感性;与其他种族的关系
2. The association of PTPN22 (rs2476601) and IL2RA (rs11594656) polymorphisms with T1D in Egyptian children [J] . Abdelrahman Hadeel M., Sherief Laila M., Elrahman Doaa M. Abd, Human Immunology: Official Journal of the American Society for Histocompatibility and Immunogenetics . 2016,第8期

机译：埃及儿童中PTPN22（rs2476601）和IL2RA（rs11594656）多态性与T1D的关联
3. TNF-α-308 promoter G/A and PTPN22 (1858 C/T) genes polymorphisms in Egyptian patients with systemic lupus erythematosus [J] . FathyM.M., KamalM.M., El-MougyF., Comparative clinical pathology . 2013,第5期

机译：埃及系统性红斑狼疮患者的TNF-α-308启动子G / A和PTPN22（1858 C / T）基因多态性
4. Single Nucleotide Polymorphisms (SNPs) in MicroRNA Processing Genes and Susceptibility to Black Carbon Effects on Cognition in a Cohort of Older Men [C] . Elena Colicino, Giulia Giuliano, Melinda Power, Annual conference of the International Society of Exposure Science . 2014

机译：MicroRNA加工基因中的单核苷酸多态性（SNP）和易受黑碳影响的老年人群认知能力的影响
5. CYP1A1 polymorphisms and genetic susceptibility to lung cancer: The roles of genotype, phenotype, and ethnicity [D] . Crofts, Frances Gayle. 1995

机译：CYP1A1基因多态性与肺癌遗传易感性：基因型，表型和种族的作用
6. TNFAIP3 Gene Polymorphisms in Three Common Autoimmune Diseases: Systemic Lupus Erythematosus Rheumatoid Arthritis and Primary Sjogren Syndrome—Association with Disease Susceptibility and Clinical Phenotypes in Italian Patients [O] . C. Ciccacci, A. Latini, C. Perricone, 2019

机译：三种常见的自身免疫性疾病中的TNFAIP3基因多态性：系统性红斑狼疮类风湿性关节炎和原发性干燥综合征—与意大利患者的疾病易感性和临床表型相关
7. PTPN22 polymorphisms, but not R620W, were associated with the genetic susceptibility of systemic lupus erythematosus and rheumatoid arthritis in a Chinese Han population [O] . Liang Tang, Yan Wang, Shui Zheng, 2016

机译：PTPN22多态性，但不是R620W，与中国汉族人群的系统性红斑狼疮和类风湿性关节炎的遗传易感性有关

IRF5, PTPN22, CD28, IL2RA, KIF5A, BLK and TNFAIP3 genes polymorphisms and lupus susceptibility in a cohort from the Egypt Delta; relation to other ethnic groups

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