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首页> 外文期刊>Vaccine >Seroprevalence of HBV in immigrant pregnant women and coverage of HBIG vaccine for neonates born to chronically infected immigrant mothers in Hsin-Chu County, Taiwan.
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Seroprevalence of HBV in immigrant pregnant women and coverage of HBIG vaccine for neonates born to chronically infected immigrant mothers in Hsin-Chu County, Taiwan.

机译：台湾新竹县孕妇的HBV血清阳性率和慢性感染移民母亲所生新生儿的HBIG疫苗覆盖率。

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摘要

This study was carried out to assess the prevalence of HBsAg positivity and coverage rate of antenatal HBV screening among immigrant women. In addition, the extent of administration of HBIG plus HB vaccine #1 to neonates born to chronically infected (HBeAg-positive/HBsAg-positive) mothers was assessed. All pregnant women residing in Hsin-Chu County, Taiwan and giving birth during 2004-2006 were recruited. Among all 16926 cases, the prevalence of HBsAg positivity according to their ethnicities was Mainland Chinese, 11.0% (68/616); Indonesian, 3.5% (15/426); Vietnamese, 7.4% (42/568); aboriginal Taiwanese, 20.6% (109/530); and non-aboriginal Taiwanese 11.5% (1536/13368). Among the HBsAg carriers, the prevalence of HBeAg positivity was Mainland Chinese, 52.9% (36/68); Indonesian, 53.3% (8/15); Vietnamese, 45.2% (19/42); aboriginal Taiwanese, 47.7% (52/109); and non-aboriginal Taiwanese, 26.8% (411/1534). With non-aboriginal Taiwanese as the reference category, results of multiple logistic regression revealed the healthy immigrant phenomenon in the HBsAg carriage state among pregnant women from Indonesia (OR 0.30; CI 95%: 0.18-0.50) and Vietnam (OR 0.68; CI 95%: 0.49-0.93). On the contrary, among chronically infected mothers, Mainland Chinese showed the highest risk for HBeAg positivity (OR 2.79; CI 95%: 1.7-4.58). More efforts should be made to improve HBV infection among aboriginal Taiwanese pregnant women who were more vulnerable to HBsAg positivity (OR 2.15; CI 95%: 1.72-2.68) and HBeAg positivity (OR 1.93; CI 95%: 1.28-2.90). Age was another independent predictor for HBsAg positivity (OR 1.02; CI 95%: 1.01-1.03) and for HBeAg positivity among chronically infected mothers (OR 0.93; CI 95%: 0.91-0.96). The coverage rates of antenatal HBV screening and HBIG plus HB vaccine #1 showed no difference among these multiple ethnic subgroups. In 2006, the overall coverage rate of antenatal HBV screening was 98.7% (5546/5639), with the individual rate being Mainland Chinese, 100% (267/267); Indonesian, 97.2% (106/109); Vietnamese, 99.5% (201/202); aboriginal Taiwanese, 97.0% (196/202); and non-aboriginal Taiwanese, 99.8% (4776/4785). The administration rate of HBIG plus HB vaccine #1 was 100% for all ethnic subgroups.
机译：本研究旨在评估移民妇女中HBsAg阳性的患病率和产前HBV筛查的覆盖率。此外，还评估了向慢性感染（HBeAg阳性/ HBsAg阳性）母亲出生的新生儿施用HBIG + HB疫苗＃1的程度。招募了所有居住在台湾新竹县并在2004-2006年期间分娩的孕妇。在所有16926例病例中，按种族划分的HBsAg阳性患病率是中国大陆人，占11.0％（68/616）。印尼文，3.5％（15/426）;越南文7.4％（42/568）;台湾原住民，20.6％（109/530）;和非土著台湾人11.5％（1536/13368）。在HBsAg携带者中，HBeAg阳性的患病率是中国大陆人，占52.9％（36/68）;印尼文，占53.3％（8/15）;越南文，45.2％（19/42）;台湾原住民，47.7％（52/109）;非土著台湾人占26.8％（411/1534）。以非原住民台湾人为参考类别，多重logistic回归结果显示印尼（OR 0.30; CI 95％：0.18-0.50）和越南（OR 0.68; CI 95）孕妇的HBsAg携带状态为健康移民现象。 ％：0.49-0.93）。相反，在慢性感染的母亲中，中国大陆人表现出最高的HBeAg阳性风险（OR 2.79; CI 95％：1.7-4.58）。台湾原住民孕妇应加大努力以改善HBV感染，这些孕妇更容易受到HBsAg阳性（OR 2.15; CI 95％：1.72-2.68）和HBeAg阳性（OR 1.93; CI 95％：1.28-2.90）。年龄是慢性感染母亲中HBsAg阳性（OR 1.02; CI 95％：1.01-1.03）和HBeAg阳性的另一个独立预测因子（OR 0.93; CI 95％：0.91-0.96）。产前HBV筛查和HBIG加HB疫苗＃1的覆盖率在这些多族裔亚组之间没有差异。 2006年，产前HBV筛查的总覆盖率为98.7％（5546/5639），其中中国大陆为100％（267/267）。印尼文，97.2％（106/109）;越南文，99.5％（201/202）;台湾原住民，97.0％（196/202）;非原住民台湾人占99.8％（4776/4785）。在所有族裔亚组中，HBIG加HB＃1疫苗的施用率均为100％。

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