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Hepatitis A control in a refugee camp by active immunization

机译:通过主动免疫控制难民营中的甲型肝炎

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An outbreak of hepatitis A occurred among children of a refugee camp in Croatia. In order to disrupt the outbreak, we decided to vaccinate children from 1 to 15 years of age in the camp, in addition to intensified general preventive measures. Assuming high prevalence of hepatitis A virus antibodies within this population, we conducted anti-HAV testing of the children eligible for vaccination. Of 108 children tested, 74 (68.50%) M ere anti-HAV positive. We vaccinated 34 children. One month after vaccination 31 previously negative children were tested for anti-HAV and 30 of them were found positive, suggesting a seroconversion rate of 96.8% One child fell ill 5 days after vaccination, after whom no new cases of hepatitis A occurred. Thus we conclude that active immunization is a successful means of stopping an outbreak of hepatitis A.
机译:克罗地亚一个难民营的儿童中爆发了甲型肝炎。为了中断疫情,我们决定在集中营中为1至15岁的儿童接种疫苗,此外还加强了总体预防措施。假设该人群中甲型肝炎病毒抗体的患病率很高,我们对有资格接种疫苗的儿童进行了抗HAV检测。在测试的108名儿童中,有74名(68.50%)的抗HAV阳性。我们为34名儿童接种了疫苗。接种后一个月,有31名先前阴性的儿童接受了抗HAV检测,结果发现其中30例呈阳性,表明血清转化率为96.8%。一名儿童在接种疫苗5天后生病,此后没有新的甲型肝炎病例发生。因此,我们得出结论,主动免疫是阻止甲型肝炎暴发的成功方法。

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