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首页> 外文期刊>Vaccine >Self-assessment of immediate post-vaccination pain after two different MMR vaccines administered as a second dose in 4- to 6-year-old children
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Self-assessment of immediate post-vaccination pain after two different MMR vaccines administered as a second dose in 4- to 6-year-old children

机译：在4至6岁的儿童中第二次接种两种不同的MMR疫苗后，立即评估接种后即刻疼痛

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The aim of this study was to compare self-reported immediate post-vaccination pain and safety of Priorix(R) versus RORVax(R) in 4- to 6-year-old children receiving their second dose of MMR vaccine, using the Faces Pain Scale-Revised (FPS-R), a validated self-report pain scale recommended by the French National Accreditation Agency and Health Evaluation. A total of 620 children from 28 French pediatricians completed all study procedures. Immediate post-vaccination pain was reported by 17.8% of the subjects in Priorix(R) group (N= 309) and by 44.7% of the subjects in RORVax(R) group (N= 311) (OR = 3.7; P < 0.001). Parents' pain scores correlated significantly with children's scores. The reduction of immediate pain incidence in Priorix(R) group persisted over the 4 post-vaccination days. This study, using a validated self-assessment pain scale, confirmed previous data showing a significantly lower incidence of immediate post-vaccination pain with Priorix(R) as compared to RORVax(R). Copyright 2004 Elsevier Ltd. All rights reserved.
机译：这项研究的目的是比较使用Faces Pain镇痛剂的4至6岁儿童的自我报告的立即接种疫苗后的疼痛和Priorix®与RORVax®的安全性。修订版量表（FPS-R）是法国国家认证局和健康评估推荐的经过验证的自我报告疼痛量表。来自28名法国儿科医生的620名儿童完成了所有学习程序。据报道，Priorix（R）组的受试者有17.8％（N = 309）和RORVax（R）组的受试者有44.7％（N = 311）（OR = 3.7; P <0.001 ）。父母的疼痛评分与孩子的评分显着相关。在疫苗接种后的4天中，Priorix（R）组的即刻疼痛发生率持续下降。这项研究使用经过验证的自我评估疼痛量表，证实了先前的数据显示，与RORVax®相比，Priorix®的即时接种后疼痛发生率显着降低。版权所有2004 ElsevierLtd。保留所有权利。

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