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Economic evaluation of vaccination against influenza in the elderly: an experience from a population-based influenza vaccination program in Taiwan

机译：老年人流感疫苗接种的经济评估：台湾基于人群的流感疫苗接种计划的经验

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摘要

Due to viral strains, influenza season, and consultations and admission rates varying from country to country, the continued economic evaluation of influenza vaccination for the elderly people aged 65 years and above is paramount, particularly in areas with dense population. Efficacy and cost-effective analysis of influenza vaccination in reducing all-cause mortality and hospitalization was therefore elucidated based on a prospective and population-based study targeted to 226,997 elderly people aged 65 years and above residing in Taipei county, Taiwan between 1 October 2000 and 31 March 2001. Vaccination against influenza for the elderly persons can lead to a 29% (95% CI: 23-35%) significant reduction of all-cause deaths. Approximately, 20% (95% CI: 9-30%) significant reduction in hospitalization was observed for average-risk group but 4% (95% CI: -4-11%) non-significant reduction for high-risk group. Community-based influenza vaccination program for elderly people aged 65 years and above was demonstrated to be effective in reducing mortality in all elderly people but not significantly in reducing hospitalization. Universal vaccination program for the elderly people seems cost-effective in averting death or gaining life years.
机译：由于病毒株，流感季节以及咨询和入院率因国家而异，因此对65岁及以上的老年人进行流感疫苗的持续经济评估至关重要，特别是在人口稠密的地区。因此，基于一项针对2000年10月1日至2000年10月1日之间居住在台湾台北县的226997名65岁及以上的老年人的前瞻性和基于人群的研究，阐明了流感疫苗接种在降低全因死亡率和住院率方面的功效和成本效益分析。 2001年3月31日。针对老年人的流感疫苗可以使全因死亡人数减少29％（95％CI：23-35％）。平均风险组大约有20％（95％CI：9-30％）的住院显着减少，而高危组则有4％（95％CI：-4-11％）的显着降低。事实证明，针对65岁及65岁以上老年人的社区流感疫苗接种计划可有效降低所有老年人的死亡率，但不能显着降低住院率。老年人的通用疫苗接种计划在避免死亡或延长寿命方面似乎具有成本效益。

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