Recombinant Salmonella vaccines for biodefence

Atkins HS; Morton M; Griffin KF; Stokes MG; Nataro JP; Titball RW

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Recombinant Salmonella vaccines for biodefence

机译：用于生物防御的重组沙门氏菌疫苗

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There is a requirement for vaccines to protect against pathogens that may be misused for bioterrorism or biowarfare purposes. In particular, biodefence vaccines are required that may be used for safe and easy immunisation of populations and that can rapidly induce mucosal immunity to provide protection at the lung surface against a range of airborne agents. To address this need, recombinant Salmonella vaccines are being developed. In this review, the technologies used, considerations needed, progress made, and future prospects for developing multivalent Salmonella-based vaccines for biodefence are discussed.

机译：需要一种疫苗来防止可能被滥用用于生物恐怖主义或生物战目的病原体。特别地，需要生物防御疫苗，其可以用于人群的安全和容易免疫，并且可以快速诱导粘膜免疫以在肺表面提供针对多种空气传播剂的保护。为了满足这种需求，正在开发重组沙门氏菌疫苗。在这篇综述中，讨论了开发用于生物防御的基于沙门氏菌的多价疫苗所使用的技术，所需的考虑因素，取得的进展以及未来的前景。

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《Vaccine》 |2006年第15期|共8页
作者
Atkins HS; Morton M; Griffin KF; Stokes MG; Nataro JP; Titball RW;
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正文语种 eng
中图分类卫生标准、卫生检查、医药管理;
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专利

1. Recombinant Salmonella vaccines for biodefence [J] . Atkins HS, Morton M, Griffin KF, Vaccine . 2006,第15期

机译：用于生物防御的重组沙门氏菌疫苗
2. Development and evaluation of candidate recombinant Salmonella-vectored Salmonella vaccines [J] . Poultry Science . 2010,第11期

机译：沙门氏菌载体重组沙门氏菌候选疫苗的开发和评估
3. Construction of a recombinant oral vaccine against Salmonella typhi and Salmonella typhimurium. [J] . Y Cao, Z Wen, D Lu Infection and immunity . 1992,第7期

机译：抗鼠伤寒沙门氏菌和鼠伤寒沙门氏菌的重组口服疫苗的构建。
4. Immunogenicity evaluation of recombinant fim-c salmonella typhi protein as typhoid vaccine candidate on wistar rat [C] . M Nurjayadi, IR Kartika, F Kumiadewi Annual Applied Science and Engineering Conference . 2019

机译：重组FIM-C沙门氏菌Typhi蛋白作为Wistar大鼠伤寒疫苗候选的免疫原性评价
5. Development of a Recombinant Attenuated Salmonella Cancer Vaccine. [D] . Hand, Nicholas. 2018

机译：重组减毒沙门氏菌疫苗的开发。
6. Combined Vaccine Regimen Based on Parenteral Priming with a DNA Vaccine and Administration of an Oral Booster Consisting of a Recombinant Salmonella enterica Serovar Typhimurium Vaccine Strain for Immunization against Infection with Human-Derived Enterotoxigenic Escherichia coli Strains [O] . Marcio O. Lásaro, Wilson B. Luiz, Maria E. Sbrogio-Almeida, 2004

机译：基于肠胃外疫苗和DNA疫苗的联合疫苗方案以及口服重组人沙门氏菌血清型鼠伤寒沙门氏菌疫苗株的口服加强免疫以抵抗人源性产肠毒素的大肠杆菌菌株的感染。
7. Combined vaccine regimen based on parenteral priming with a DNA vaccine and administration of an oral booster consisting of a recombinant Salmonella enterica serovar typhimurium vaccine strain for immunization against infection with human-derived enterotoxigenic Escherichia coli strains [O] . Lasaro Marcio O., Luiz Wilson B., Sbrogio-Almeida Maria E., 2004

机译：基于肠胃外引物的联合疫苗方案与DNA疫苗的组合，并给予由重组沙门氏菌血清型鼠伤寒沙门氏菌疫苗菌株组成的口服加强疫苗，以免疫人源性产肠毒素的大肠杆菌菌株

Recombinant Salmonella vaccines for biodefence

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